LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PIK-93
0.04
uM
LJP5
 72
hr
 1657 5721 5588 1.0242 1.0272
BT-20 PIK-93
0.12
uM
LJP5
 72
hr
 1657 5535 5588 0.9907 0.9893
BT-20 PIK-93
0.37
uM
LJP5
 72
hr
 1657 5886 5588 1.0536 1.0605
BT-20 PIK-93
1.11
uM
LJP5
 72
hr
 1657 5534 5588 0.9904 0.9889
BT-20 PIK-93
3.33
uM
LJP5
 72
hr
 1657 4260 5588 0.7626 0.7135
BT-20 PIK-93
10
uM
LJP5
 72
hr
 1657 2006 5588 0.3592 0.1149
BT-20 Dactolisib
0.04
uM
LJP5
 72
hr
 1657 2762 5588 0.4942 0.3378
BT-20 Dactolisib
0.12
uM
LJP5
 72
hr
 1657 2346 5588 0.4198 0.2190
BT-20 Dactolisib
0.37
uM
LJP5
 72
hr
 1657 2155 5588 0.3857 0.1612
BT-20 Dactolisib
1.11
uM
LJP5
 72
hr
 1657 1960 5588 0.3508 0.1003
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1657 1806 5588 0.3233 0.0503
BT-20 Dactolisib
10
uM
LJP5
 72
hr
 1657 1976 5588 0.3538 0.1056
BT-20 Alpelisib
0.04
uM
LJP5
 72
hr
 1657 5760 5588 1.0307 1.0347
BT-20 Alpelisib
0.12
uM
LJP5
 72
hr
 1657 5235 5588 0.9369 0.9267
BT-20 Alpelisib
0.37
uM
LJP5
 72
hr
 1657 4172 5588 0.7466 0.6926
BT-20 Alpelisib
1.11
uM
LJP5
 72
hr
 1657 3680 5588 0.6586 0.5758
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1657 2120 5588 0.3796 0.1505
BT-20 Alpelisib
10
uM
LJP5
 72
hr
 1657 1445 5588 0.2586 -0.0753
BT-20 GDC-0980
0.04
uM
LJP5
 72
hr
 1657 3126 5588 0.5595 0.4360
BT-20 GDC-0980
0.12
uM
LJP5
 72
hr
 1657 2054 5588 0.3677 0.1303
BT-20 GDC-0980
0.37
uM
LJP5
 72
hr
 1657 1608 5588 0.2879 -0.0175
BT-20 GDC-0980
1.11
uM
LJP5
 72
hr
 1657 1407 5588 0.2518 -0.0893
BT-20 GDC-0980
3.33
uM
LJP5
 72
hr
 1657 1279 5588 0.2290 -0.1376
BT-20 GDC-0980
10
uM
LJP5
 72
hr
 1657 1222 5588 0.2188 -0.1597
BT-20 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1657 2816 5588 0.5042 0.3524