LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1657 | 3193 | 5383 | 0.5937 | 0.4715 |
BT-20 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1866 | 5383 | 0.3465 | 0.0714 |
BT-20 | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1519 | 5383 | 0.2821 | -0.0506 |
BT-20 | JNK-9L | 10 | uM | LJP6 | 72 | hr | 1657 | 1246 | 5383 | 0.2316 | -0.1549 |
BT-20 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5590 | 5588 | 1.0004 | 1.0004 |
BT-20 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4960 | 5383 | 0.9209 | 0.9044 |
BT-20 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5016 | 5588 | 0.8977 | 0.8803 |
BT-20 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4941 | 5383 | 0.9177 | 0.9012 |
BT-20 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5192 | 5588 | 0.9293 | 0.9180 |
BT-20 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 4997 | 5383 | 0.9278 | 0.9129 |
BT-20 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4787 | 5588 | 0.8570 | 0.8311 |
BT-20 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4352 | 5383 | 0.8077 | 0.7621 |
BT-20 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4039 | 5588 | 0.7231 | 0.6622 |
BT-20 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 3503 | 5383 | 0.6501 | 0.5514 |
BT-20 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 1657 | 3192 | 5588 | 0.5715 | 0.4532 |
BT-20 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 1657 | 3157 | 5383 | 0.5864 | 0.4604 |
BT-20 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1657 | 2646 | 5588 | 0.4735 | 0.3043 |
BT-20 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2703 | 5383 | 0.5021 | 0.3329 |
BT-20 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1657 | 1971 | 5588 | 0.3529 | 0.1035 |
BT-20 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1657 | 1888 | 5383 | 0.3511 | 0.0800 |
BT-20 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1657 | 1776 | 5588 | 0.3179 | 0.0400 |
BT-20 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1657 | 1855 | 5383 | 0.3447 | 0.0682 |
BT-20 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1657 | 1916 | 5588 | 0.3429 | 0.0861 |
BT-20 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1894 | 5383 | 0.3522 | 0.0819 |
BT-20 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1735 | 5588 | 0.3106 | 0.0264 |