LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1656 | 5383 | 0.3076 | -0.0009 |
BT-20 | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 1657 | 1357 | 5588 | 0.2430 | -0.1081 |
BT-20 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 1657 | 1353 | 5383 | 0.2513 | -0.1133 |
BT-20 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5842 | 5588 | 1.0453 | 1.0508 |
BT-20 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5446 | 5588 | 0.9746 | 0.9707 |
BT-20 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5135 | 5588 | 0.9188 | 0.9047 |
BT-20 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4646 | 5588 | 0.8315 | 0.7992 |
BT-20 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3958 | 5588 | 0.7082 | 0.6424 |
BT-20 | YM 201636 | 10 | uM | LJP5 | 72 | hr | 1657 | 2142 | 5588 | 0.3833 | 0.1571 |
BT-20 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5554 | 5588 | 0.9939 | 0.9923 |
BT-20 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5347 | 5588 | 0.9573 | 0.9502 |
BT-20 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5466 | 5588 | 0.9782 | 0.9748 |
BT-20 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5383 | 5588 | 0.9632 | 0.9572 |
BT-20 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4467 | 5588 | 0.7995 | 0.7594 |
BT-20 | TWS119 | 10 | uM | LJP5 | 72 | hr | 1657 | 1933 | 5588 | 0.3459 | 0.0915 |
BT-20 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5142 | 5588 | 0.9205 | 0.9077 |
BT-20 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5322 | 5588 | 0.9525 | 0.9451 |
BT-20 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5327 | 5588 | 0.9534 | 0.9462 |
BT-20 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5220 | 5588 | 0.9344 | 0.9241 |
BT-20 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4574 | 5588 | 0.8186 | 0.7841 |
BT-20 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1657 | 2114 | 5588 | 0.3784 | 0.1488 |
BT-20 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5401 | 5588 | 0.9668 | 0.9618 |
BT-20 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5165 | 5588 | 0.9244 | 0.9122 |
BT-20 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5405 | 5588 | 0.9673 | 0.9624 |
BT-20 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4768 | 5588 | 0.8532 | 0.8267 |