LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 LDN-193189
3.33
uM
LJP5
 72
hr
 1657 2144 5588 0.3839 0.1577
BT-20 LDN-193189
10
uM
LJP5
 72
hr
 1657 545 5588 0.0977 -0.4702
BT-20 PF431396
0.04
uM
LJP5
 72
hr
 1657 4925 5588 0.8820 0.8558
BT-20 PF431396
0.12
uM
LJP5
 72
hr
 1657 4657 5588 0.8335 0.8026
BT-20 PF431396
0.37
uM
LJP5
 72
hr
 1657 3504 5588 0.6271 0.5313
BT-20 PF431396
1.11
uM
LJP5
 72
hr
 1657 2395 5588 0.4285 0.2330
BT-20 PF431396
3.33
uM
LJP5
 72
hr
 1657 1940 5588 0.3473 0.0939
BT-20 PF431396
10
uM
LJP5
 72
hr
 1657 1706 5588 0.3054 0.0163
BT-20 Celastrol
0.04
uM
LJP6
 72
hr
 1657 5828 5383 1.0827 1.0958
BT-20 Celastrol
0.12
uM
LJP6
 72
hr
 1657 5995 5383 1.1135 1.1305
BT-20 Celastrol
0.37
uM
LJP6
 72
hr
 1657 4608 5383 0.8559 0.8248
BT-20 Celastrol
1.11
uM
LJP6
 72
hr
 1657 2358 5383 0.4376 0.2285
BT-20 Celastrol
3.33
uM
LJP6
 72
hr
 1657 860 5383 0.1598 -0.3212
BT-20 Celastrol
10
uM
LJP6
 72
hr
 1657 890 5383 0.1652 -0.3073
BT-20 SU11274
0.04
uM
LJP5
 72
hr
 1657 5686 5588 1.0175 1.0199
BT-20 SU11274
0.12
uM
LJP5
 72
hr
 1657 5749 5588 1.0291 1.0329
BT-20 SU11274
0.37
uM
LJP5
 72
hr
 1657 5441 5588 0.9738 0.9700
BT-20 SU11274
1.11
uM
LJP5
 72
hr
 1657 5287 5588 0.9465 0.9378
BT-20 SU11274
3.33
uM
LJP5
 72
hr
 1657 4682 5588 0.8379 0.8081
BT-20 SU11274
10
uM
LJP5
 72
hr
 1657 2093 5588 0.3746 0.1423
BT-20 Canertinib
0.04
uM
LJP6
 72
hr
 1657 4885 5383 0.9074 0.8883
BT-20 Canertinib
0.12
uM
LJP6
 72
hr
 1657 4875 5383 0.9054 0.8861
BT-20 Canertinib
0.37
uM
LJP6
 72
hr
 1657 4568 5383 0.8489 0.8163
BT-20 Canertinib
1.11
uM
LJP6
 72
hr
 1657 4617 5383 0.8580 0.8278
BT-20 Canertinib
3.33
uM
LJP6
 72
hr
 1657 4017 5383 0.7469 0.6844