LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Withaferin A
0.12
uM
LJP5
 72
hr
 1657 5464 5588 0.9778 0.9745
BT-20 Withaferin A
0.12
uM
LJP6
 72
hr
 1657 5355 5383 0.9948 0.9939
BT-20 Withaferin A
0.37
uM
LJP5
 72
hr
 1657 4776 5588 0.8548 0.8279
BT-20 Withaferin A
0.37
uM
LJP6
 72
hr
 1657 4431 5383 0.8240 0.7847
BT-20 Withaferin A
1.11
uM
LJP5
 72
hr
 1657 1430 5588 0.2561 -0.0807
BT-20 Withaferin A
1.11
uM
LJP6
 72
hr
 1657 1303 5383 0.2420 -0.1329
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1657 907 5588 0.1626 -0.2916
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1657 901 5383 0.1669 -0.3048
BT-20 Withaferin A
10
uM
LJP5
 72
hr
 1657 933 5588 0.1671 -0.2796
BT-20 Withaferin A
10
uM
LJP6
 72
hr
 1657 931 5383 0.1726 -0.2909
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 929 3284 3237 1.0145 1.0160
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 929 3309 3237 1.0220 1.0242
Hs 578T Seliciclib
0.37
uM
LJP5
 72
hr
 929 3143 3237 0.9708 0.9669
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 929 3131 3237 0.9672 0.9632
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 929 3177 3237 0.9814 0.9793
Hs 578T Seliciclib
10
uM
LJP5
 72
hr
 929 2538 3237 0.7840 0.7468
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 929 3200 3216 0.9948 0.9941
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 929 2782 3216 0.8649 0.8442
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 929 967 3216 0.3006 0.0222
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 929 868 3216 0.2699 -0.0374
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 929 737 3216 0.2291 -0.1227
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 929 616 3216 0.1917 -0.2056
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 929 1764 3216 0.5485 0.4302
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 929 1262 3216 0.3923 0.1853
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 929 1146 3216 0.3564 0.1243