LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1657 2752 5383 0.5113 0.3462
BT-20 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1657 2032 5588 0.3637 0.1229
BT-20 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1657 2049 5383 0.3809 0.1327
BT-20 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1657 1726 5588 0.3091 0.0233
BT-20 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1657 1719 5383 0.3197 0.0219
BT-20 Mitoxantrone
1.11
uM
LJP5
 72
hr
 1657 1493 5588 0.2674 -0.0580
BT-20 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1657 1471 5383 0.2731 -0.0687
BT-20 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1657 1389 5588 0.2489 -0.0974
BT-20 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1657 1288 5383 0.2391 -0.1397
BT-20 Mitoxantrone
10
uM
LJP5
 72
hr
 1657 1047 5588 0.1876 -0.2323
BT-20 Mitoxantrone
10
uM
LJP6
 72
hr
 1657 924 5383 0.1714 -0.2929
BT-20 Radicicol
0.04
uM
LJP5
 72
hr
 1657 5049 5588 0.9035 0.8873
BT-20 Radicicol
0.04
uM
LJP6
 72
hr
 1657 4818 5383 0.8962 0.8754
BT-20 Radicicol
0.12
uM
LJP5
 72
hr
 1657 3436 5588 0.6150 0.5157
BT-20 Radicicol
0.12
uM
LJP6
 72
hr
 1657 3337 5383 0.6204 0.5100
BT-20 Radicicol
0.37
uM
LJP5
 72
hr
 1657 2239 5588 0.4007 0.1870
BT-20 Radicicol
0.37
uM
LJP6
 72
hr
 1657 2251 5383 0.4185 0.1976
BT-20 Radicicol
1.11
uM
LJP5
 72
hr
 1657 1892 5588 0.3385 0.0780
BT-20 Radicicol
1.11
uM
LJP6
 72
hr
 1657 1936 5383 0.3602 0.0960
BT-20 Radicicol
3.33
uM
LJP5
 72
hr
 1657 1834 5588 0.3284 0.0596
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1657 1848 5383 0.3434 0.0660
BT-20 Radicicol
10
uM
LJP5
 72
hr
 1657 1506 5588 0.2697 -0.0531
BT-20 Radicicol
10
uM
LJP6
 72
hr
 1657 1525 5383 0.2833 -0.0482
BT-20 Withaferin A
0.04
uM
LJP5
 72
hr
 1657 5694 5588 1.0191 1.0212
BT-20 Withaferin A
0.04
uM
LJP6
 72
hr
 1657 5684 5383 1.0565 1.0662