LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 2897 | 5383 | 0.5381 | 0.3885 |
BT-20 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 2386 | 5383 | 0.4432 | 0.2383 |
BT-20 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 1495 | 5383 | 0.2781 | -0.0588 |
BT-20 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1225 | 5383 | 0.2275 | -0.1638 |
BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1142 | 5383 | 0.2118 | -0.1988 |
BT-20 | A443654 | 10 | uM | LJP6 | 72 | hr | 1657 | 652 | 5383 | 0.1212 | -0.4241 |
BT-20 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5376 | 5588 | 0.9625 | 0.9564 |
BT-20 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5393 | 5588 | 0.9651 | 0.9598 |
BT-20 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5431 | 5588 | 0.9717 | 0.9670 |
BT-20 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5406 | 5588 | 0.9674 | 0.9620 |
BT-20 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5640 | 5588 | 1.0094 | 1.0107 |
BT-20 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1657 | 5018 | 5588 | 0.8981 | 0.8811 |
BT-20 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4409 | 5383 | 0.8193 | 0.7780 |
BT-20 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4346 | 5383 | 0.8071 | 0.7625 |
BT-20 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1657 | 3203 | 5383 | 0.5953 | 0.4737 |
BT-20 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 2331 | 5383 | 0.4327 | 0.2207 |
BT-20 | Pictilisib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1746 | 5383 | 0.3245 | 0.0309 |
BT-20 | Pictilisib | 10 | uM | LJP6 | 72 | hr | 1657 | 1554 | 5383 | 0.2885 | -0.0387 |
BT-20 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5766 | 5588 | 1.0318 | 1.0360 |
BT-20 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5799 | 5588 | 1.0376 | 1.0417 |
BT-20 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5388 | 5588 | 0.9645 | 0.9590 |
BT-20 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5512 | 5588 | 0.9864 | 0.9842 |
BT-20 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5398 | 5588 | 0.9662 | 0.9612 |
BT-20 | PD184352 | 10 | uM | LJP5 | 72 | hr | 1657 | 2987 | 5588 | 0.5346 | 0.3991 |
BT-20 | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5745 | 5588 | 1.0281 | 1.0319 |