LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PLX-4720
0.12
uM
LJP5
72
hr
1657 5379 5588 0.9628 0.9571
BT-20 PLX-4720
0.37
uM
LJP5
72
hr
1657 5485 5588 0.9816 0.9790
BT-20 PLX-4720
1.11
uM
LJP5
72
hr
1657 5517 5588 0.9873 0.9855
BT-20 PLX-4720
3.33
uM
LJP5
72
hr
1657 4095 5588 0.7329 0.6750
BT-20 PLX-4720
10
uM
LJP5
72
hr
1657 2924 5588 0.5234 0.3819
BT-20 Lapatinib
0.04
uM
LJP6
72
hr
1657 4984 5383 0.9258 0.9105
BT-20 Lapatinib
0.12
uM
LJP6
72
hr
1657 5262 5383 0.9770 0.9722
BT-20 Lapatinib
0.37
uM
LJP6
72
hr
1657 5384 5383 1.0007 1.0011
BT-20 Lapatinib
1.11
uM
LJP6
72
hr
1657 5117 5383 0.9507 0.9413
BT-20 Lapatinib
3.33
uM
LJP6
72
hr
1657 4868 5383 0.9041 0.8840
BT-20 Lapatinib
10
uM
LJP6
72
hr
1657 4252 5383 0.7908 0.7422
BT-20 Sirolimus
0.04
uM
LJP6
72
hr
1657 3525 5383 0.6554 0.5597
BT-20 Sirolimus
0.12
uM
LJP6
72
hr
1657 3617 5383 0.6724 0.5833
BT-20 Sirolimus
0.37
uM
LJP6
72
hr
1657 3629 5383 0.6752 0.5868
BT-20 Sirolimus
1.11
uM
LJP6
72
hr
1657 3685 5383 0.6853 0.6009
BT-20 Sirolimus
3.33
uM
LJP6
72
hr
1657 3676 5383 0.6839 0.5987
BT-20 Sirolimus
10
uM
LJP6
72
hr
1657 3799 5383 0.7058 0.6292
BT-20 ZSTK474
0.04
uM
LJP6
72
hr
1657 5377 5383 0.9997 1.0001
BT-20 ZSTK474
0.12
uM
LJP6
72
hr
1657 4895 5383 0.9102 0.8926
BT-20 ZSTK474
0.37
uM
LJP6
72
hr
1657 3379 5383 0.6290 0.5217
BT-20 ZSTK474
1.11
uM
LJP6
72
hr
1657 2187 5383 0.4063 0.1764
BT-20 ZSTK474
3.33
uM
LJP6
72
hr
1657 1697 5383 0.3153 0.0134
BT-20 ZSTK474
10
uM
LJP6
72
hr
1657 1543 5383 0.2861 -0.0439
BT-20 BX-912
0.04
uM
LJP5
72
hr
1657 5063 5588 0.9063 0.8906
BT-20 BX-912
0.12
uM
LJP5
72
hr
1657 5125 5588 0.9174 0.9041