LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5379 | 5588 | 0.9628 | 0.9571 |
BT-20 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5485 | 5588 | 0.9816 | 0.9790 |
BT-20 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5517 | 5588 | 0.9873 | 0.9855 |
BT-20 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4095 | 5588 | 0.7329 | 0.6750 |
BT-20 | PLX-4720 | 10 | uM | LJP5 | 72 | hr | 1657 | 2924 | 5588 | 0.5234 | 0.3819 |
BT-20 | Lapatinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4984 | 5383 | 0.9258 | 0.9105 |
BT-20 | Lapatinib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5262 | 5383 | 0.9770 | 0.9722 |
BT-20 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1657 | 5384 | 5383 | 1.0007 | 1.0011 |
BT-20 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5117 | 5383 | 0.9507 | 0.9413 |
BT-20 | Lapatinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4868 | 5383 | 0.9041 | 0.8840 |
BT-20 | Lapatinib | 10 | uM | LJP6 | 72 | hr | 1657 | 4252 | 5383 | 0.7908 | 0.7422 |
BT-20 | Sirolimus | 0.04 | uM | LJP6 | 72 | hr | 1657 | 3525 | 5383 | 0.6554 | 0.5597 |
BT-20 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1657 | 3617 | 5383 | 0.6724 | 0.5833 |
BT-20 | Sirolimus | 0.37 | uM | LJP6 | 72 | hr | 1657 | 3629 | 5383 | 0.6752 | 0.5868 |
BT-20 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1657 | 3685 | 5383 | 0.6853 | 0.6009 |
BT-20 | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 1657 | 3676 | 5383 | 0.6839 | 0.5987 |
BT-20 | Sirolimus | 10 | uM | LJP6 | 72 | hr | 1657 | 3799 | 5383 | 0.7058 | 0.6292 |
BT-20 | ZSTK474 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5377 | 5383 | 0.9997 | 1.0001 |
BT-20 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4895 | 5383 | 0.9102 | 0.8926 |
BT-20 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 3379 | 5383 | 0.6290 | 0.5217 |
BT-20 | ZSTK474 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 2187 | 5383 | 0.4063 | 0.1764 |
BT-20 | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1697 | 5383 | 0.3153 | 0.0134 |
BT-20 | ZSTK474 | 10 | uM | LJP6 | 72 | hr | 1657 | 1543 | 5383 | 0.2861 | -0.0439 |
BT-20 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5063 | 5588 | 0.9063 | 0.8906 |
BT-20 | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5125 | 5588 | 0.9174 | 0.9041 |