LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Canertinib
10
uM
LJP6
 72
hr
 1657 1183 5383 0.2198 -0.1810
BT-20 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1657 5806 5588 1.0395 1.0444
BT-20 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1657 5821 5588 1.0417 1.0470
BT-20 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1657 5765 5588 1.0319 1.0357
BT-20 NVP-AEW541
1.11
uM
LJP5
 72
hr
 1657 5604 5588 1.0032 1.0034
BT-20 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1657 5837 5588 1.0449 1.0507
BT-20 NVP-AEW541
10
uM
LJP5
 72
hr
 1657 5335 5588 0.9547 0.9472
BT-20 PHA-665752
0.04
uM
LJP5
 72
hr
 1657 5634 5588 1.0085 1.0095
BT-20 PHA-665752
0.12
uM
LJP5
 72
hr
 1657 5904 5588 1.0568 1.0639
BT-20 PHA-665752
0.37
uM
LJP5
 72
hr
 1657 5605 5588 1.0030 1.0029
BT-20 PHA-665752
1.11
uM
LJP5
 72
hr
 1657 5697 5588 1.0198 1.0224
BT-20 PHA-665752
3.33
uM
LJP5
 72
hr
 1657 5638 5588 1.0088 1.0098
BT-20 PHA-665752
10
uM
LJP5
 72
hr
 1657 4059 5588 0.7264 0.6666
BT-20 PI103
0.04
uM
LJP6
 72
hr
 1657 5425 5383 1.0075 1.0087
BT-20 PI103
0.12
uM
LJP6
 72
hr
 1657 4398 5383 0.8180 0.7771
BT-20 PI103
0.37
uM
LJP6
 72
hr
 1657 2581 5383 0.4799 0.2982
BT-20 PI103
1.11
uM
LJP6
 72
hr
 1657 1749 5383 0.3248 0.0315
BT-20 PI103
3.33
uM
LJP6
 72
hr
 1657 1552 5383 0.2885 -0.0380
BT-20 PI103
10
uM
LJP6
 72
hr
 1657 1434 5383 0.2665 -0.0818
BT-20 Dovitinib
0.04
uM
LJP5
 72
hr
 1657 4715 5588 0.8437 0.8140
BT-20 Dovitinib
0.12
uM
LJP5
 72
hr
 1657 4026 5588 0.7202 0.6570
BT-20 Dovitinib
0.37
uM
LJP5
 72
hr
 1657 3165 5588 0.5661 0.4396
BT-20 Dovitinib
1.11
uM
LJP5
 72
hr
 1657 2850 5588 0.5098 0.3598
BT-20 Dovitinib
3.33
uM
LJP5
 72
hr
 1657 2475 5588 0.4428 0.2558
BT-20 Dovitinib
10
uM
LJP5
 72
hr
 1657 2575 5588 0.4609 0.2855