LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | GSK 690693 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4744 | 5588 | 0.8493 | 0.8218 |
BT-20 | GSK 690693 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 4599 | 5588 | 0.8232 | 0.7890 |
BT-20 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 4300 | 5588 | 0.7694 | 0.7219 |
BT-20 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 3817 | 5588 | 0.6833 | 0.6093 |
BT-20 | GSK 690693 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3450 | 5588 | 0.6175 | 0.5187 |
BT-20 | GSK 690693 | 10 | uM | LJP5 | 72 | hr | 1657 | 3072 | 5588 | 0.5500 | 0.4220 |
BT-20 | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4651 | 5383 | 0.8645 | 0.8359 |
BT-20 | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 1617 | 5383 | 0.3006 | -0.0143 |
BT-20 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 1197 | 5383 | 0.2226 | -0.1742 |
BT-20 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1048 | 5383 | 0.1950 | -0.2366 |
BT-20 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 1037 | 5383 | 0.1925 | -0.2425 |
BT-20 | SNS-032 | 10 | uM | LJP6 | 72 | hr | 1657 | 1155 | 5383 | 0.2147 | -0.1917 |
BT-20 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 3980 | 5383 | 0.7400 | 0.6753 |
BT-20 | Afatinib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4514 | 5383 | 0.8387 | 0.8034 |
BT-20 | Afatinib | 0.37 | uM | LJP6 | 72 | hr | 1657 | 4690 | 5383 | 0.8712 | 0.8428 |
BT-20 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5087 | 5383 | 0.9459 | 0.9359 |
BT-20 | Afatinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4854 | 5383 | 0.9034 | 0.8832 |
BT-20 | Afatinib | 10 | uM | LJP6 | 72 | hr | 1657 | 1569 | 5383 | 0.2917 | -0.0317 |
BT-20 | GSK1904529A | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4830 | 5383 | 0.8982 | 0.8776 |
BT-20 | GSK1904529A | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4877 | 5383 | 0.9056 | 0.8860 |
BT-20 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1657 | 5067 | 5383 | 0.9418 | 0.9307 |
BT-20 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5222 | 5383 | 0.9705 | 0.9654 |
BT-20 | GSK1904529A | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5204 | 5383 | 0.9668 | 0.9607 |
BT-20 | GSK1904529A | 10 | uM | LJP6 | 72 | hr | 1657 | 5435 | 5383 | 1.0102 | 1.0125 |
BT-20 | Linsitinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4776 | 5588 | 0.8550 | 0.8287 |