LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
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BT-20 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 3685 | 5588 | 0.6595 | 0.5767 |
BT-20 | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 2144 | 5588 | 0.3837 | 0.1578 |
BT-20 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 1965 | 5588 | 0.3516 | 0.1015 |
BT-20 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1958 | 5588 | 0.3504 | 0.0995 |
BT-20 | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 1657 | 1812 | 5588 | 0.3242 | 0.0513 |
BT-20 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4819 | 5588 | 0.8626 | 0.8379 |
BT-20 | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5003 | 5588 | 0.8953 | 0.8778 |
BT-20 | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5023 | 5588 | 0.8990 | 0.8819 |
BT-20 | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4901 | 5588 | 0.8771 | 0.8557 |
BT-20 | Erlotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 4827 | 5588 | 0.8639 | 0.8398 |
BT-20 | Erlotinib | 10 | uM | LJP5 | 72 | hr | 1657 | 3520 | 5588 | 0.6297 | 0.5354 |
BT-20 | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5762 | 5383 | 1.0708 | 1.0826 |
BT-20 | Gefitinib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5388 | 5383 | 1.0024 | 1.0031 |
BT-20 | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 1657 | 5237 | 5383 | 0.9742 | 0.9698 |
BT-20 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5052 | 5383 | 0.9391 | 0.9271 |
BT-20 | Gefitinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4857 | 5383 | 0.9029 | 0.8836 |
BT-20 | Gefitinib | 10 | uM | LJP6 | 72 | hr | 1657 | 4280 | 5383 | 0.7955 | 0.7482 |
BT-20 | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5364 | 5588 | 0.9598 | 0.9534 |
BT-20 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5401 | 5588 | 0.9666 | 0.9617 |
BT-20 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1657 | 5513 | 5588 | 0.9865 | 0.9840 |
BT-20 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 5335 | 5588 | 0.9547 | 0.9477 |
BT-20 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 5576 | 5588 | 0.9977 | 0.9966 |
BT-20 | Nilotinib | 10 | uM | LJP5 | 72 | hr | 1657 | 2060 | 5588 | 0.3687 | 0.1314 |
BT-20 | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 1657 | 4504 | 5383 | 0.8372 | 0.8010 |
BT-20 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1657 | 4144 | 5383 | 0.7704 | 0.7156 |