LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 XMD16-144
0.12
uM
LJP5
72
hr
1657 3685 5588 0.6595 0.5767
BT-20 XMD16-144
0.37
uM
LJP5
72
hr
1657 2144 5588 0.3837 0.1578
BT-20 XMD16-144
1.11
uM
LJP5
72
hr
1657 1965 5588 0.3516 0.1015
BT-20 XMD16-144
3.33
uM
LJP5
72
hr
1657 1958 5588 0.3504 0.0995
BT-20 XMD16-144
10
uM
LJP5
72
hr
1657 1812 5588 0.3242 0.0513
BT-20 Erlotinib
0.04
uM
LJP5
72
hr
1657 4819 5588 0.8626 0.8379
BT-20 Erlotinib
0.12
uM
LJP5
72
hr
1657 5003 5588 0.8953 0.8778
BT-20 Erlotinib
0.37
uM
LJP5
72
hr
1657 5023 5588 0.8990 0.8819
BT-20 Erlotinib
1.11
uM
LJP5
72
hr
1657 4901 5588 0.8771 0.8557
BT-20 Erlotinib
3.33
uM
LJP5
72
hr
1657 4827 5588 0.8639 0.8398
BT-20 Erlotinib
10
uM
LJP5
72
hr
1657 3520 5588 0.6297 0.5354
BT-20 Gefitinib
0.04
uM
LJP6
72
hr
1657 5762 5383 1.0708 1.0826
BT-20 Gefitinib
0.12
uM
LJP6
72
hr
1657 5388 5383 1.0024 1.0031
BT-20 Gefitinib
0.37
uM
LJP6
72
hr
1657 5237 5383 0.9742 0.9698
BT-20 Gefitinib
1.11
uM
LJP6
72
hr
1657 5052 5383 0.9391 0.9271
BT-20 Gefitinib
3.33
uM
LJP6
72
hr
1657 4857 5383 0.9029 0.8836
BT-20 Gefitinib
10
uM
LJP6
72
hr
1657 4280 5383 0.7955 0.7482
BT-20 Nilotinib
0.04
uM
LJP5
72
hr
1657 5364 5588 0.9598 0.9534
BT-20 Nilotinib
0.12
uM
LJP5
72
hr
1657 5401 5588 0.9666 0.9617
BT-20 Nilotinib
0.37
uM
LJP5
72
hr
1657 5513 5588 0.9865 0.9840
BT-20 Nilotinib
1.11
uM
LJP5
72
hr
1657 5335 5588 0.9547 0.9477
BT-20 Nilotinib
3.33
uM
LJP5
72
hr
1657 5576 5588 0.9977 0.9966
BT-20 Nilotinib
10
uM
LJP5
72
hr
1657 2060 5588 0.3687 0.1314
BT-20 JNK-9L
0.04
uM
LJP6
72
hr
1657 4504 5383 0.8372 0.8010
BT-20 JNK-9L
0.12
uM
LJP6
72
hr
1657 4144 5383 0.7704 0.7156