LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 GSK1059615
0.37
uM
LJP6
 72
hr
 1657 1728 5383 0.3209 0.0237
BT-20 GSK1059615
1.11
uM
LJP5
 72
hr
 1657 1221 5588 0.2186 -0.1599
BT-20 GSK1059615
1.11
uM
LJP6
 72
hr
 1657 1366 5383 0.2534 -0.1095
BT-20 GSK1059615
3.33
uM
LJP5
 72
hr
 1657 968 5588 0.1734 -0.2667
BT-20 GSK1059615
3.33
uM
LJP6
 72
hr
 1657 1111 5383 0.2062 -0.2114
BT-20 GSK1059615
10
uM
LJP5
 72
hr
 1657 772 5588 0.1384 -0.3536
BT-20 GSK1059615
10
uM
LJP6
 72
hr
 1657 837 5383 0.1553 -0.3320
BT-20 Brivanib
0.04
uM
LJP5
 72
hr
 1657 5266 5588 0.9423 0.9333
BT-20 Brivanib
0.12
uM
LJP5
 72
hr
 1657 5301 5588 0.9487 0.9408
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1657 5313 5588 0.9511 0.9436
BT-20 Brivanib
1.11
uM
LJP5
 72
hr
 1657 5152 5588 0.9223 0.9093
BT-20 Brivanib
3.33
uM
LJP5
 72
hr
 1657 4970 5588 0.8897 0.8710
BT-20 Brivanib
10
uM
LJP5
 72
hr
 1657 4549 5588 0.8140 0.7785
BT-20 CHIR-99021
0.04
uM
LJP6
 72
hr
 1657 5553 5383 1.0324 1.0384
BT-20 CHIR-99021
0.12
uM
LJP6
 72
hr
 1657 5492 5383 1.0202 1.0236
BT-20 CHIR-99021
0.37
uM
LJP6
 72
hr
 1657 5511 5383 1.0241 1.0286
BT-20 CHIR-99021
1.11
uM
LJP6
 72
hr
 1657 5500 5383 1.0214 1.0247
BT-20 CHIR-99021
3.33
uM
LJP6
 72
hr
 1657 5559 5383 1.0324 1.0376
BT-20 CHIR-99021
10
uM
LJP6
 72
hr
 1657 4839 5383 0.9001 0.8802
BT-20 Linifanib
0.04
uM
LJP6
 72
hr
 1657 5888 5383 1.0944 1.1096
BT-20 Linifanib
0.12
uM
LJP6
 72
hr
 1657 5763 5383 1.0714 1.0832
BT-20 Linifanib
0.37
uM
LJP6
 72
hr
 1657 5855 5383 1.0887 1.1031
BT-20 Linifanib
1.11
uM
LJP6
 72
hr
 1657 5860 5383 1.0896 1.1043
BT-20 Linifanib
3.33
uM
LJP6
 72
hr
 1657 5543 5383 1.0295 1.0343
BT-20 Linifanib
10
uM
LJP6
 72
hr
 1657 2877 5383 0.5350 0.3839