LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5631 | 5383 | 1.0467 | 1.0550 |
BT-20 | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5506 | 5383 | 1.0233 | 1.0276 |
BT-20 | Imatinib | 10 | uM | LJP6 | 72 | hr | 1657 | 5268 | 5383 | 0.9791 | 0.9755 |
BT-20 | NVP-TAE684 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5496 | 5383 | 1.0213 | 1.0252 |
BT-20 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 3725 | 5383 | 0.6928 | 0.6115 |
BT-20 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 4956 | 5383 | 0.9217 | 0.9062 |
BT-20 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4275 | 5383 | 0.7947 | 0.7470 |
BT-20 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 2649 | 5383 | 0.4922 | 0.3172 |
BT-20 | NVP-TAE684 | 10 | uM | LJP6 | 72 | hr | 1657 | 1604 | 5383 | 0.2983 | -0.0192 |
BT-20 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1657 | 5524 | 5588 | 0.9885 | 0.9862 |
BT-20 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 1217 | 5383 | 0.2262 | -0.1665 |
BT-20 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1657 | 1844 | 5588 | 0.3301 | 0.0627 |
BT-20 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 1028 | 5383 | 0.1914 | -0.2451 |
BT-20 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1657 | 1541 | 5588 | 0.2758 | -0.0409 |
BT-20 | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 1032 | 5383 | 0.1921 | -0.2434 |
BT-20 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1657 | 1516 | 5588 | 0.2713 | -0.0497 |
BT-20 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 1035 | 5383 | 0.1926 | -0.2420 |
BT-20 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1657 | 1342 | 5588 | 0.2401 | -0.1137 |
BT-20 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 931 | 5383 | 0.1731 | -0.2880 |
BT-20 | CGP60474 | 10 | uM | LJP5 | 72 | hr | 1657 | 1176 | 5588 | 0.2103 | -0.1793 |
BT-20 | CGP60474 | 10 | uM | LJP6 | 72 | hr | 1657 | 673 | 5383 | 0.1252 | -0.4116 |
BT-20 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 6043 | 5383 | 1.1238 | 1.1429 |
BT-20 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5982 | 5383 | 1.1120 | 1.1295 |
BT-20 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 6106 | 5383 | 1.1349 | 1.1551 |
BT-20 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 6376 | 5383 | 1.1852 | 1.2109 |