LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1657 4627 5383 0.8592 0.8286
BT-20 JW-7-24-1
1.11
uM
LJP6
 72
hr
 1657 4510 5383 0.8379 0.8023
BT-20 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1657 4050 5383 0.7525 0.6918
BT-20 JW-7-24-1
10
uM
LJP6
 72
hr
 1657 1813 5383 0.3368 0.0536
BT-20 Dasatinib
0.04
uM
LJP5
 72
hr
 1657 5156 5588 0.9227 0.9103
BT-20 Dasatinib
0.04
uM
LJP6
 72
hr
 1657 2745 5383 0.5113 0.3461
BT-20 Dasatinib
0.12
uM
LJP5
 72
hr
 1657 3500 5588 0.6268 0.5308
BT-20 Dasatinib
0.12
uM
LJP6
 72
hr
 1657 1833 5383 0.3410 0.0613
BT-20 Dasatinib
0.37
uM
LJP5
 72
hr
 1657 1894 5588 0.3390 0.0787
BT-20 Dasatinib
0.37
uM
LJP6
 72
hr
 1657 1678 5383 0.3121 0.0071
BT-20 Dasatinib
1.11
uM
LJP5
 72
hr
 1657 1580 5588 0.2828 -0.0271
BT-20 Dasatinib
1.11
uM
LJP6
 72
hr
 1657 1453 5383 0.2706 -0.0749
BT-20 Dasatinib
3.33
uM
LJP5
 72
hr
 1657 1332 5588 0.2384 -0.1176
BT-20 Dasatinib
3.33
uM
LJP6
 72
hr
 1657 1159 5383 0.2156 -0.1899
BT-20 Dasatinib
10
uM
LJP5
 72
hr
 1657 1283 5588 0.2298 -0.1359
BT-20 Dasatinib
10
uM
LJP6
 72
hr
 1657 1008 5383 0.1878 -0.2541
BT-20 Tozasertib
0.04
uM
LJP5
 72
hr
 1657 3346 5588 0.5989 0.4915
BT-20 Tozasertib
0.12
uM
LJP5
 72
hr
 1657 1979 5588 0.3543 0.1056
BT-20 Tozasertib
0.37
uM
LJP5
 72
hr
 1657 1709 5588 0.3059 0.0175
BT-20 Tozasertib
1.11
uM
LJP5
 72
hr
 1657 1732 5588 0.3099 0.0252
BT-20 Tozasertib
3.33
uM
LJP5
 72
hr
 1657 1627 5588 0.2912 -0.0108
BT-20 Tozasertib
10
uM
LJP5
 72
hr
 1657 1660 5588 0.2971 0.0008
BT-20 Imatinib
0.04
uM
LJP6
 72
hr
 1657 5484 5383 1.0200 1.0236
BT-20 Imatinib
0.12
uM
LJP6
 72
hr
 1657 5758 5383 1.0700 1.0813
BT-20 Imatinib
0.37
uM
LJP6
 72
hr
 1657 5458 5383 1.0140 1.0164