LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 6371 | 5383 | 1.1849 | 1.2102 |
BT-20 | PD173074 | 10 | uM | LJP6 | 72 | hr | 1657 | 5503 | 5383 | 1.0229 | 1.0271 |
BT-20 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1657 | 4615 | 5588 | 0.8261 | 0.7934 |
BT-20 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1657 | 5034 | 5588 | 0.9007 | 0.8840 |
BT-20 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 1657 | 4808 | 5588 | 0.8603 | 0.8351 |
BT-20 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1657 | 4527 | 5588 | 0.8101 | 0.7735 |
BT-20 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1657 | 3569 | 5588 | 0.6389 | 0.5488 |
BT-20 | Crizotinib | 10 | uM | LJP5 | 72 | hr | 1657 | 1646 | 5588 | 0.2946 | -0.0041 |
BT-20 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5435 | 5383 | 1.0104 | 1.0127 |
BT-20 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5506 | 5383 | 1.0235 | 1.0279 |
BT-20 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 5520 | 5383 | 1.0256 | 1.0302 |
BT-20 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4882 | 5383 | 0.9072 | 0.8879 |
BT-20 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 4482 | 5383 | 0.8337 | 0.7971 |
BT-20 | BMS345541 | 10 | uM | LJP6 | 72 | hr | 1657 | 1686 | 5383 | 0.3135 | 0.0101 |
BT-20 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5295 | 5383 | 0.9838 | 0.9810 |
BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5203 | 5383 | 0.9661 | 0.9591 |
BT-20 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1657 | 5458 | 5383 | 1.0146 | 1.0177 |
BT-20 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1657 | 5417 | 5383 | 1.0066 | 1.0079 |
BT-20 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1657 | 5475 | 5383 | 1.0170 | 1.0199 |
BT-20 | KIN001-043 | 10 | uM | LJP6 | 72 | hr | 1657 | 3221 | 5383 | 0.5978 | 0.4766 |
BT-20 | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1657 | 5648 | 5383 | 1.0488 | 1.0562 |
BT-20 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1657 | 5246 | 5383 | 0.9750 | 0.9706 |
BT-20 | Saracatinib | 0.37 | uM | LJP6 | 72 | hr | 1657 | 4894 | 5383 | 0.9091 | 0.8904 |
BT-20 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1657 | 4346 | 5383 | 0.8059 | 0.7591 |
BT-20 | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 1657 | 3616 | 5383 | 0.6712 | 0.5806 |