LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PD173074
3.33
uM
LJP6
72
hr
1657 6371 5383 1.1849 1.2102
BT-20 PD173074
10
uM
LJP6
72
hr
1657 5503 5383 1.0229 1.0271
BT-20 Crizotinib
0.04
uM
LJP5
72
hr
1657 4615 5588 0.8261 0.7934
BT-20 Crizotinib
0.12
uM
LJP5
72
hr
1657 5034 5588 0.9007 0.8840
BT-20 Crizotinib
0.37
uM
LJP5
72
hr
1657 4808 5588 0.8603 0.8351
BT-20 Crizotinib
1.11
uM
LJP5
72
hr
1657 4527 5588 0.8101 0.7735
BT-20 Crizotinib
3.33
uM
LJP5
72
hr
1657 3569 5588 0.6389 0.5488
BT-20 Crizotinib
10
uM
LJP5
72
hr
1657 1646 5588 0.2946 -0.0041
BT-20 BMS345541
0.04
uM
LJP6
72
hr
1657 5435 5383 1.0104 1.0127
BT-20 BMS345541
0.12
uM
LJP6
72
hr
1657 5506 5383 1.0235 1.0279
BT-20 BMS345541
0.37
uM
LJP6
72
hr
1657 5520 5383 1.0256 1.0302
BT-20 BMS345541
1.11
uM
LJP6
72
hr
1657 4882 5383 0.9072 0.8879
BT-20 BMS345541
3.33
uM
LJP6
72
hr
1657 4482 5383 0.8337 0.7971
BT-20 BMS345541
10
uM
LJP6
72
hr
1657 1686 5383 0.3135 0.0101
BT-20 KIN001-043
0.04
uM
LJP6
72
hr
1657 5295 5383 0.9838 0.9810
BT-20 KIN001-043
0.12
uM
LJP6
72
hr
1657 5203 5383 0.9661 0.9591
BT-20 KIN001-043
0.37
uM
LJP6
72
hr
1657 5458 5383 1.0146 1.0177
BT-20 KIN001-043
1.11
uM
LJP6
72
hr
1657 5417 5383 1.0066 1.0079
BT-20 KIN001-043
3.33
uM
LJP6
72
hr
1657 5475 5383 1.0170 1.0199
BT-20 KIN001-043
10
uM
LJP6
72
hr
1657 3221 5383 0.5978 0.4766
BT-20 Saracatinib
0.04
uM
LJP6
72
hr
1657 5648 5383 1.0488 1.0562
BT-20 Saracatinib
0.12
uM
LJP6
72
hr
1657 5246 5383 0.9750 0.9706
BT-20 Saracatinib
0.37
uM
LJP6
72
hr
1657 4894 5383 0.9091 0.8904
BT-20 Saracatinib
1.11
uM
LJP6
72
hr
1657 4346 5383 0.8059 0.7591
BT-20 Saracatinib
3.33
uM
LJP6
72
hr
1657 3616 5383 0.6712 0.5806