LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Palbociclib
0.37
uM
LJP6
 72
hr
 929 1791 3216 0.5569 0.4424
Hs 578T Palbociclib
1.11
uM
LJP6
 72
hr
 929 1645 3216 0.5116 0.3757
Hs 578T Palbociclib
3.33
uM
LJP6
 72
hr
 929 1645 3216 0.5114 0.3755
Hs 578T Palbociclib
10
uM
LJP6
 72
hr
 929 1563 3216 0.4862 0.3371
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 929 2878 3216 0.8949 0.8798
Hs 578T PF562271
0.12
uM
LJP6
 72
hr
 929 2628 3216 0.8170 0.7861
Hs 578T PF562271
0.37
uM
LJP6
 72
hr
 929 2472 3216 0.7686 0.7266
Hs 578T PF562271
1.11
uM
LJP6
 72
hr
 929 2142 3216 0.6661 0.5940
Hs 578T PF562271
3.33
uM
LJP6
 72
hr
 929 1906 3216 0.5929 0.4933
Hs 578T PF562271
10
uM
LJP6
 72
hr
 929 918 3216 0.2855 -0.0068
Hs 578T PHA-793887
0.04
uM
LJP6
 72
hr
 929 2039 3216 0.6341 0.5509
Hs 578T PHA-793887
0.12
uM
LJP6
 72
hr
 929 1947 3216 0.6056 0.5116
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 929 1593 3216 0.4953 0.3511
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 929 1246 3216 0.3875 0.1781
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 929 1057 3216 0.3288 0.0749
Hs 578T PHA-793887
10
uM
LJP6
 72
hr
 929 836 3216 0.2598 -0.0582
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 929 2741 3216 0.8521 0.8288
Hs 578T QL-X-138
0.12
uM
LJP6
 72
hr
 929 2453 3216 0.7627 0.7192
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 929 2212 3216 0.6878 0.6226
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 929 1970 3216 0.6124 0.5209
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 929 1786 3216 0.5555 0.4402
Hs 578T QL-X-138
10
uM
LJP6
 72
hr
 929 980 3216 0.3047 0.0301
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 929 3047 3216 0.9476 0.9408
Hs 578T QL-XII-47
0.12
uM
LJP6
 72
hr
 929 3032 3216 0.9426 0.9351
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 929 2623 3216 0.8157 0.7850