LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Vemurafenib
3.33
uM
LJP5
 72
hr
 1657 5138 5588 0.9195 0.9061
BT-20 Vemurafenib
10
uM
LJP5
 72
hr
 1657 3848 5588 0.6890 0.6163
BT-20 Enzastaurin
0.04
uM
LJP5
 72
hr
 1657 6123 5588 1.0960 1.1073
BT-20 Enzastaurin
0.12
uM
LJP5
 72
hr
 1657 5937 5588 1.0629 1.0706
BT-20 Enzastaurin
0.37
uM
LJP5
 72
hr
 1657 6128 5588 1.0967 1.1082
BT-20 Enzastaurin
1.11
uM
LJP5
 72
hr
 1657 6392 5588 1.1441 1.1597
BT-20 Enzastaurin
3.33
uM
LJP5
 72
hr
 1657 6589 5588 1.1796 1.1970
BT-20 Enzastaurin
10
uM
LJP5
 72
hr
 1657 6867 5588 1.2290 1.2497
BT-20 Palbociclib
0.04
uM
LJP6
 72
hr
 1657 4057 5383 0.7531 0.6916
BT-20 Palbociclib
0.12
uM
LJP6
 72
hr
 1657 3420 5383 0.6351 0.5302
BT-20 Palbociclib
0.37
uM
LJP6
 72
hr
 1657 2900 5383 0.5388 0.3897
BT-20 Palbociclib
1.11
uM
LJP6
 72
hr
 1657 2553 5383 0.4744 0.2891
BT-20 Palbociclib
3.33
uM
LJP6
 72
hr
 1657 2405 5383 0.4464 0.2433
BT-20 Palbociclib
10
uM
LJP6
 72
hr
 1657 2337 5383 0.4341 0.2235
BT-20 PF562271
0.04
uM
LJP6
 72
hr
 1657 5018 5383 0.9312 0.9164
BT-20 PF562271
0.12
uM
LJP6
 72
hr
 1657 4735 5383 0.8788 0.8523
BT-20 PF562271
0.37
uM
LJP6
 72
hr
 1657 4473 5383 0.8304 0.7921
BT-20 PF562271
1.11
uM
LJP6
 72
hr
 1657 3445 5383 0.6387 0.5333
BT-20 PF562271
3.33
uM
LJP6
 72
hr
 1657 1962 5383 0.3646 0.1040
BT-20 PF562271
10
uM
LJP6
 72
hr
 1657 1301 5383 0.2415 -0.1346
BT-20 PHA-793887
0.04
uM
LJP6
 72
hr
 1657 3101 5383 0.5762 0.4456
BT-20 PHA-793887
0.12
uM
LJP6
 72
hr
 1657 2954 5383 0.5480 0.4020
BT-20 PHA-793887
0.37
uM
LJP6
 72
hr
 1657 2536 5383 0.4705 0.2818
BT-20 PHA-793887
1.11
uM
LJP6
 72
hr
 1657 1984 5383 0.3678 0.1079
BT-20 PHA-793887
3.33
uM
LJP6
 72
hr
 1657 1654 5383 0.3068 -0.0030