LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PF477736
0.04
uM
LJP5
 72
hr
 868 2965 3410 0.8681 0.8589
MDA-MB-231 PF477736
0.12
uM
LJP5
 72
hr
 868 3069 3410 0.8999 0.8955
MDA-MB-231 PF477736
0.37
uM
LJP5
 72
hr
 868 2622 3410 0.7678 0.7480
MDA-MB-231 PF477736
1.11
uM
LJP5
 72
hr
 868 1921 3410 0.5630 0.4942
MDA-MB-231 PF477736
3.33
uM
LJP5
 72
hr
 868 1360 3410 0.3983 0.2536
MDA-MB-231 PF477736
10
uM
LJP5
 72
hr
 868 1078 3410 0.3162 0.1156
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 72
hr
 868 3684 3410 1.0805 1.0802
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 72
hr
 868 3525 3410 1.0339 1.0342
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 72
hr
 868 3428 3410 1.0060 1.0054
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 72
hr
 868 2550 3410 0.7479 0.7245
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 72
hr
 868 1081 3410 0.3162 0.1119
MDA-MB-231 LDN-193189
10
uM
LJP5
 72
hr
 868 332 3410 0.0973 -0.3860
MDA-MB-231 PF431396
0.04
uM
LJP5
 72
hr
 868 3329 3410 0.9768 0.9767
MDA-MB-231 PF431396
0.12
uM
LJP5
 72
hr
 868 2949 3410 0.8658 0.8593
MDA-MB-231 PF431396
0.37
uM
LJP5
 72
hr
 868 2233 3410 0.6555 0.6146
MDA-MB-231 PF431396
1.11
uM
LJP5
 72
hr
 868 1645 3410 0.4827 0.3826
MDA-MB-231 PF431396
3.33
uM
LJP5
 72
hr
 868 1354 3410 0.3973 0.2527
MDA-MB-231 PF431396
10
uM
LJP5
 72
hr
 868 882 3410 0.2586 0.0074
MDA-MB-231 Celastrol
0.04
uM
LJP6
 72
hr
 868 3721 3556 1.0474 1.0454
MDA-MB-231 Celastrol
0.12
uM
LJP6
 72
hr
 868 3735 3556 1.0507 1.0492
MDA-MB-231 Celastrol
0.37
uM
LJP6
 72
hr
 868 2005 3556 0.5647 0.5100
MDA-MB-231 Celastrol
1.11
uM
LJP6
 72
hr
 868 877 3556 0.2467 0.0044
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 868 692 3556 0.1945 -0.1062
MDA-MB-231 Celastrol
10
uM
LJP6
 72
hr
 868 402 3556 0.1136 -0.3153
MDA-MB-231 SU11274
0.04
uM
LJP5
 72
hr
 868 3885 3410 1.1393 1.1365