LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PD0325901
10
uM
LJP6
 72
hr
 868 826 3556 0.2325 -0.0260
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 72
hr
 868 1313 3410 0.3844 0.2312
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 72
hr
 868 1639 3556 0.4613 0.3662
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 72
hr
 868 1081 3410 0.3174 0.1178
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 72
hr
 868 1227 3556 0.3449 0.1847
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 72
hr
 868 1240 3410 0.3639 0.1982
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 72
hr
 868 1323 3556 0.3721 0.2300
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 72
hr
 868 1062 3410 0.3119 0.1079
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 72
hr
 868 1172 3556 0.3294 0.1580
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 72
hr
 868 859 3410 0.2526 -0.0053
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 868 964 3556 0.2713 0.0513
MDA-MB-231 Geldanamycin
10
uM
LJP5
 72
hr
 868 603 3410 0.1773 -0.1688
MDA-MB-231 Geldanamycin
10
uM
LJP6
 72
hr
 868 555 3556 0.1563 -0.1974
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 868 3606 3410 1.0563 1.0541
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 868 3322 3410 0.9724 0.9688
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 868 3142 3410 0.9205 0.9165
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 868 2841 3410 0.8328 0.8224
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 868 2657 3410 0.7798 0.7633
MDA-MB-231 YM 201636
10
uM
LJP5
 72
hr
 868 1597 3410 0.4688 0.3619
MDA-MB-231 TWS119
0.04
uM
LJP5
 72
hr
 868 3371 3410 0.9878 0.9868
MDA-MB-231 TWS119
0.12
uM
LJP5
 72
hr
 868 3524 3410 1.0327 1.0323
MDA-MB-231 TWS119
0.37
uM
LJP5
 72
hr
 868 3464 3410 1.0158 1.0160
MDA-MB-231 TWS119
1.11
uM
LJP5
 72
hr
 868 2921 3410 0.8566 0.8493
MDA-MB-231 TWS119
3.33
uM
LJP5
 72
hr
 868 2263 3410 0.6627 0.6181
MDA-MB-231 TWS119
10
uM
LJP5
 72
hr
 868 866 3410 0.2541 -0.0022