LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 72
hr
 868 3848 3556 1.0816 1.0783
MDA-MB-231 Gefitinib
10
uM
LJP6
 72
hr
 868 3151 3556 0.8859 0.8842
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 72
hr
 868 3097 3410 0.9077 0.9037
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 72
hr
 868 2785 3410 0.8164 0.8039
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 72
hr
 868 2617 3410 0.7666 0.7470
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 72
hr
 868 2314 3410 0.6774 0.6394
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 72
hr
 868 2376 3410 0.6960 0.6633
MDA-MB-231 Nilotinib
10
uM
LJP5
 72
hr
 868 1235 3410 0.3619 0.1942
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 72
hr
 868 2621 3556 0.7375 0.7219
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 72
hr
 868 2466 3556 0.6942 0.6709
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 72
hr
 868 1999 3556 0.5629 0.5068
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 72
hr
 868 1223 3556 0.3434 0.1816
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 72
hr
 868 850 3556 0.2392 -0.0103
MDA-MB-231 JNK-9L
10
uM
LJP6
 72
hr
 868 831 3556 0.2336 -0.0219
MDA-MB-231 PD0325901
0.04
uM
LJP5
 72
hr
 868 2123 3410 0.6227 0.5731
MDA-MB-231 PD0325901
0.04
uM
LJP6
 72
hr
 868 2204 3556 0.6188 0.5778
MDA-MB-231 PD0325901
0.12
uM
LJP5
 72
hr
 868 1728 3410 0.5064 0.4162
MDA-MB-231 PD0325901
0.12
uM
LJP6
 72
hr
 868 1754 3556 0.4940 0.4135
MDA-MB-231 PD0325901
0.37
uM
LJP5
 72
hr
 868 1473 3410 0.4318 0.3050
MDA-MB-231 PD0325901
0.37
uM
LJP6
 72
hr
 868 1384 3556 0.3891 0.2570
MDA-MB-231 PD0325901
1.11
uM
LJP5
 72
hr
 868 1235 3410 0.3625 0.1956
MDA-MB-231 PD0325901
1.11
uM
LJP6
 72
hr
 868 1020 3556 0.2868 0.0820
MDA-MB-231 PD0325901
3.33
uM
LJP5
 72
hr
 868 941 3410 0.2755 0.0378
MDA-MB-231 PD0325901
3.33
uM
LJP6
 72
hr
 868 861 3556 0.2422 -0.0049
MDA-MB-231 PD0325901
10
uM
LJP5
 72
hr
 868 898 3410 0.2631 0.0164