LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PIK-93 | 10 | uM | LJP5 | 72 | hr | 1476 | 1681 | 3772 | 0.4458 | 0.1003 |
| SK-BR-3 | Dactolisib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1802 | 3772 | 0.4776 | 0.1574 |
| SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1762 | 3772 | 0.4672 | 0.1394 |
| SK-BR-3 | Dactolisib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1629 | 3772 | 0.4319 | 0.0750 |
| SK-BR-3 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1605 | 3772 | 0.4254 | 0.0630 |
| SK-BR-3 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1444 | 3772 | 0.3828 | -0.0170 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 72 | hr | 1476 | 1602 | 3772 | 0.4249 | 0.0623 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3411 | 3772 | 0.9042 | 0.8561 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3174 | 3772 | 0.8417 | 0.7608 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2846 | 3772 | 0.7545 | 0.6238 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2575 | 3772 | 0.6829 | 0.5087 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2012 | 3772 | 0.5338 | 0.2573 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 72 | hr | 1476 | 1181 | 3772 | 0.3133 | -0.1523 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1768 | 3772 | 0.4687 | 0.1419 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1495 | 3772 | 0.3965 | 0.0094 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1475 | 3772 | 0.3911 | -0.0008 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1395 | 3772 | 0.3696 | -0.0420 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1498 | 3772 | 0.3971 | 0.0105 |
| SK-BR-3 | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 1476 | 1434 | 3772 | 0.3801 | -0.0221 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1493 | 3772 | 0.3960 | 0.0079 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1490 | 3643 | 0.4085 | 0.0036 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1596 | 3772 | 0.4233 | 0.0594 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1531 | 3643 | 0.4212 | 0.0285 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1603 | 3772 | 0.4250 | 0.0626 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1556 | 3643 | 0.4268 | 0.0382 |