LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1496 | 3772 | 0.3966 | 0.0091 |
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1313 | 3643 | 0.3610 | -0.0870 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1476 | 998 | 3772 | 0.2649 | -0.2515 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1082 | 3643 | 0.2962 | -0.2162 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1476 | 630 | 3772 | 0.1671 | -0.4674 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 1476 | 544 | 3643 | 0.1497 | -0.5368 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2137 | 3772 | 0.5665 | 0.3137 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2022 | 3643 | 0.5561 | 0.2741 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1766 | 3772 | 0.4682 | 0.1408 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1744 | 3643 | 0.4803 | 0.1380 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1683 | 3772 | 0.4462 | 0.1008 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1644 | 3643 | 0.4522 | 0.0862 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1697 | 3772 | 0.4499 | 0.1075 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1577 | 3643 | 0.4335 | 0.0513 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1575 | 3772 | 0.4175 | 0.0484 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1532 | 3643 | 0.4201 | 0.0252 |
| SK-BR-3 | Radicicol | 10 | uM | LJP5 | 72 | hr | 1476 | 1213 | 3772 | 0.3217 | -0.1352 |
| SK-BR-3 | Radicicol | 10 | uM | LJP6 | 72 | hr | 1476 | 1124 | 3643 | 0.3113 | -0.1876 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3835 | 3772 | 1.0169 | 1.0249 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3774 | 3643 | 1.0354 | 1.0527 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3448 | 3772 | 0.9137 | 0.8692 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3180 | 3643 | 0.8726 | 0.7997 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1592 | 3772 | 0.4222 | 0.0571 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1417 | 3643 | 0.3884 | -0.0349 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1392 | 3772 | 0.3690 | -0.0432 |