LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3667 | 3772 | 0.9721 | 0.9583 |
| SK-BR-3 | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3299 | 3772 | 0.8747 | 0.8114 |
| SK-BR-3 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3060 | 3772 | 0.8113 | 0.7132 |
| SK-BR-3 | YM 201636 | 10 | uM | LJP5 | 72 | hr | 1476 | 1748 | 3772 | 0.4634 | 0.1327 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3872 | 3772 | 1.0262 | 1.0380 |
| SK-BR-3 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3734 | 3772 | 0.9899 | 0.9846 |
| SK-BR-3 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3796 | 3772 | 1.0066 | 1.0095 |
| SK-BR-3 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3778 | 3772 | 1.0016 | 1.0014 |
| SK-BR-3 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2449 | 3772 | 0.6491 | 0.4530 |
| SK-BR-3 | TWS119 | 10 | uM | LJP5 | 72 | hr | 1476 | 1148 | 3772 | 0.3044 | -0.1719 |
| SK-BR-3 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1745 | 3772 | 0.4627 | 0.1310 |
| SK-BR-3 | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1678 | 3772 | 0.4450 | 0.0994 |
| SK-BR-3 | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1407 | 3772 | 0.3731 | -0.0353 |
| SK-BR-3 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1409 | 3772 | 0.3737 | -0.0339 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1343 | 3772 | 0.3560 | -0.0680 |
| SK-BR-3 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1476 | 1410 | 3772 | 0.3736 | -0.0347 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3944 | 3772 | 1.0455 | 1.0661 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4191 | 3772 | 1.1110 | 1.1614 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4182 | 3772 | 1.1088 | 1.1588 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3658 | 3772 | 0.9697 | 0.9537 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1055 | 3772 | 0.2796 | -0.2214 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1476 | 662 | 3772 | 0.1758 | -0.4476 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3883 | 3772 | 1.0294 | 1.0433 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2696 | 3772 | 0.7149 | 0.5605 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2147 | 3772 | 0.5694 | 0.3186 |