LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Sigma A6730 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2723 | 3772 | 0.7221 | 0.5720 |
| SK-BR-3 | Sigma A6730 | 10 | uM | LJP5 | 72 | hr | 1476 | 2085 | 3772 | 0.5531 | 0.2908 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3842 | 3772 | 1.0185 | 1.0256 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3473 | 3772 | 0.9204 | 0.8795 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3321 | 3772 | 0.8803 | 0.8188 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3096 | 3772 | 0.8209 | 0.7281 |
| SK-BR-3 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2686 | 3772 | 0.7120 | 0.5556 |
| SK-BR-3 | WH-4-025 | 10 | uM | LJP5 | 72 | hr | 1476 | 1188 | 3772 | 0.3150 | -0.1484 |
| SK-BR-3 | R406 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3838 | 3643 | 1.0554 | 1.0878 |
| SK-BR-3 | R406 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3694 | 3643 | 1.0152 | 1.0253 |
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3826 | 3643 | 1.0525 | 1.0844 |
| SK-BR-3 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4206 | 3643 | 1.1578 | 1.2443 |
| SK-BR-3 | R406 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 4165 | 3643 | 1.1424 | 1.2146 |
| SK-BR-3 | R406 | 10 | uM | LJP6 | 72 | hr | 1476 | 2765 | 3643 | 0.7602 | 0.6209 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1485 | 3643 | 0.4078 | 0.0029 |
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1434 | 3643 | 0.3943 | -0.0229 |
| SK-BR-3 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1596 | 3643 | 0.4385 | 0.0603 |
| SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1546 | 3643 | 0.4256 | 0.0368 |
| SK-BR-3 | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1426 | 3643 | 0.3925 | -0.0259 |
| SK-BR-3 | BI-2536 | 10 | uM | LJP6 | 72 | hr | 1476 | 1415 | 3643 | 0.3897 | -0.0318 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1173 | 3643 | 0.3221 | -0.1636 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1235 | 3643 | 0.3408 | -0.1267 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1118 | 3643 | 0.3073 | -0.1935 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1195 | 3643 | 0.3289 | -0.1499 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1070 | 3643 | 0.2936 | -0.2211 |