LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2462 | 3772 | 0.6528 | 0.4593 |
| SK-BR-3 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1842 | 3772 | 0.4883 | 0.1772 |
| SK-BR-3 | Crizotinib | 10 | uM | LJP5 | 72 | hr | 1476 | 1094 | 3772 | 0.2902 | -0.1986 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3872 | 3643 | 1.0634 | 1.0981 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3870 | 3643 | 1.0647 | 1.1029 |
| SK-BR-3 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3784 | 3643 | 1.0379 | 1.0568 |
| SK-BR-3 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2615 | 3643 | 0.7195 | 0.5542 |
| SK-BR-3 | BMS345541 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1820 | 3643 | 0.5004 | 0.1744 |
| SK-BR-3 | BMS345541 | 10 | uM | LJP6 | 72 | hr | 1476 | 1195 | 3643 | 0.3279 | -0.1522 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3706 | 3643 | 1.0165 | 1.0238 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3490 | 3643 | 0.9568 | 0.9309 |
| SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3120 | 3643 | 0.8574 | 0.7777 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3008 | 3643 | 0.8272 | 0.7302 |
| SK-BR-3 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 3028 | 3643 | 0.8320 | 0.7373 |
| SK-BR-3 | KIN001-043 | 10 | uM | LJP6 | 72 | hr | 1476 | 1722 | 3643 | 0.4732 | 0.1247 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4233 | 3643 | 1.1657 | 1.2572 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 4158 | 3643 | 1.1448 | 1.2253 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3815 | 3643 | 1.0498 | 1.0808 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3385 | 3643 | 0.9317 | 0.8968 |
| SK-BR-3 | Saracatinib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 3032 | 3643 | 0.8342 | 0.7421 |
| SK-BR-3 | Saracatinib | 10 | uM | LJP6 | 72 | hr | 1476 | 1968 | 3643 | 0.5423 | 0.2500 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2787 | 3772 | 0.7390 | 0.5991 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3064 | 3772 | 0.8122 | 0.7147 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3176 | 3772 | 0.8420 | 0.7614 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2618 | 3772 | 0.6939 | 0.5265 |