LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD 5438
10
uM
LJP6
 72
hr
 1235 381 4056 0.0939 -0.4975
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1235 4756 4267 1.1142 1.1242
MCF7 Pelitinib
0.12
uM
LJP5
 72
hr
 1235 4915 4267 1.1518 1.1635
MCF7 Pelitinib
0.37
uM
LJP5
 72
hr
 1235 4330 4267 1.0134 1.0128
MCF7 Pelitinib
1.11
uM
LJP5
 72
hr
 1235 3706 4267 0.8687 0.8485
MCF7 Pelitinib
3.33
uM
LJP5
 72
hr
 1235 1938 4267 0.4541 0.2857
MCF7 Pelitinib
10
uM
LJP5
 72
hr
 1235 1082 4267 0.2544 -0.0717
MCF7 Luminespib
0.04
uM
LJP5
 72
hr
 1235 1452 4267 0.3403 0.0942
MCF7 Luminespib
0.12
uM
LJP5
 72
hr
 1235 1413 4267 0.3313 0.0776
MCF7 Luminespib
0.37
uM
LJP5
 72
hr
 1235 1473 4267 0.3449 0.1023
MCF7 Luminespib
1.11
uM
LJP5
 72
hr
 1235 1481 4267 0.3472 0.1066
MCF7 Luminespib
3.33
uM
LJP5
 72
hr
 1235 1388 4267 0.3255 0.0673
MCF7 Luminespib
10
uM
LJP5
 72
hr
 1235 1233 4267 0.2888 -0.0019
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1235 1989 4267 0.4666 0.3050
MCF7 AZD8330
0.12
uM
LJP5
 72
hr
 1235 1986 4267 0.4658 0.3043
MCF7 AZD8330
0.37
uM
LJP5
 72
hr
 1235 2089 4267 0.4901 0.3419
MCF7 AZD8330
1.11
uM
LJP5
 72
hr
 1235 2392 4267 0.5606 0.4452
MCF7 AZD8330
3.33
uM
LJP5
 72
hr
 1235 2321 4267 0.5438 0.4219
MCF7 AZD8330
10
uM
LJP5
 72
hr
 1235 2532 4267 0.5932 0.4930
MCF7 TGX221
0.04
uM
LJP5
 72
hr
 1235 3428 4267 0.8030 0.7685
MCF7 TGX221
0.12
uM
LJP5
 72
hr
 1235 3633 4267 0.8513 0.8272
MCF7 TGX221
0.37
uM
LJP5
 72
hr
 1235 4070 4267 0.9549 0.9495
MCF7 TGX221
1.11
uM
LJP5
 72
hr
 1235 4179 4267 0.9788 0.9746
MCF7 TGX221
3.33
uM
LJP5
 72
hr
 1235 3227 4267 0.7558 0.7092
MCF7 TGX221
10
uM
LJP5
 72
hr
 1235 3775 4267 0.8846 0.8672