LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1160 | 4267 | 0.2724 | -0.0343 |
MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1086 | 4267 | 0.2549 | -0.0692 |
MCF7 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1143 | 4267 | 0.2681 | -0.0424 |
MCF7 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1153 | 4267 | 0.2701 | -0.0385 |
MCF7 | Torin2 | 10 | uM | LJP5 | 72 | hr | 1235 | 943 | 4267 | 0.2213 | -0.1404 |
MCF7 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3090 | 4056 | 0.7619 | 0.7066 |
MCF7 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2859 | 4056 | 0.7050 | 0.6311 |
MCF7 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2493 | 4056 | 0.6147 | 0.5057 |
MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2094 | 4056 | 0.5164 | 0.3604 |
MCF7 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1848 | 4056 | 0.4560 | 0.2647 |
MCF7 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 1235 | 895 | 4056 | 0.2208 | -0.1713 |
MCF7 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 751 | 4267 | 0.1766 | -0.2435 |
MCF7 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 827 | 4267 | 0.1939 | -0.2030 |
MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 883 | 4267 | 0.2072 | -0.1710 |
MCF7 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 904 | 4267 | 0.2117 | -0.1614 |
MCF7 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 824 | 4267 | 0.1934 | -0.2026 |
MCF7 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 1235 | 716 | 4267 | 0.1680 | -0.2638 |
MCF7 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3637 | 4056 | 0.8968 | 0.8765 |
MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3303 | 4056 | 0.8140 | 0.7725 |
MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 2730 | 4056 | 0.6737 | 0.5864 |
MCF7 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 2030 | 4056 | 0.5005 | 0.3358 |
MCF7 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1660 | 4056 | 0.4094 | 0.1880 |
MCF7 | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 1235 | 1327 | 4056 | 0.3273 | 0.0427 |
MCF7 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3319 | 4056 | 0.8179 | 0.7785 |
MCF7 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1235 | 3496 | 4056 | 0.8623 | 0.8344 |