LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 GSK1059615
0.04
uM
LJP5
 72
hr
 1235 4288 4267 1.0052 1.0057
MCF7 GSK1059615
0.04
uM
LJP6
 72
hr
 1235 4166 4056 1.0273 1.0317
MCF7 GSK1059615
0.12
uM
LJP5
 72
hr
 1235 3935 4267 0.9227 0.9120
MCF7 GSK1059615
0.12
uM
LJP6
 72
hr
 1235 3305 4056 0.8160 0.7755
MCF7 GSK1059615
0.37
uM
LJP5
 72
hr
 1235 2598 4267 0.6096 0.5160
MCF7 GSK1059615
0.37
uM
LJP6
 72
hr
 1235 2508 4056 0.6191 0.5115
MCF7 GSK1059615
1.11
uM
LJP5
 72
hr
 1235 1668 4267 0.3908 0.1821
MCF7 GSK1059615
1.11
uM
LJP6
 72
hr
 1235 1706 4056 0.4209 0.2071
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1235 1063 4267 0.2495 -0.0803
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1235 1156 4056 0.2852 -0.0380
MCF7 GSK1059615
10
uM
LJP5
 72
hr
 1235 768 4267 0.1803 -0.2331
MCF7 GSK1059615
10
uM
LJP6
 72
hr
 1235 724 4056 0.1785 -0.2680
MCF7 Brivanib
0.04
uM
LJP5
 72
hr
 1235 3555 4267 0.8335 0.8063
MCF7 Brivanib
0.12
uM
LJP5
 72
hr
 1235 3502 4267 0.8212 0.7913
MCF7 Brivanib
0.37
uM
LJP5
 72
hr
 1235 3561 4267 0.8351 0.8084
MCF7 Brivanib
1.11
uM
LJP5
 72
hr
 1235 3667 4267 0.8596 0.8365
MCF7 Brivanib
3.33
uM
LJP5
 72
hr
 1235 3966 4267 0.9283 0.9169
MCF7 Brivanib
10
uM
LJP5
 72
hr
 1235 3638 4267 0.8515 0.8263
MCF7 CHIR-99021
0.04
uM
LJP6
 72
hr
 1235 3565 4056 0.8789 0.8549
MCF7 CHIR-99021
0.12
uM
LJP6
 72
hr
 1235 3240 4056 0.7996 0.7552
MCF7 CHIR-99021
0.37
uM
LJP6
 72
hr
 1235 3231 4056 0.7964 0.7514
MCF7 CHIR-99021
1.11
uM
LJP6
 72
hr
 1235 2455 4056 0.6060 0.4928
MCF7 CHIR-99021
3.33
uM
LJP6
 72
hr
 1235 2493 4056 0.6151 0.5063
MCF7 CHIR-99021
10
uM
LJP6
 72
hr
 1235 1624 4056 0.4006 0.1714
MCF7 Linifanib
0.04
uM
LJP6
 72
hr
 1235 4787 4056 1.1804 1.2033