LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3700 | 3643 | 1.0172 | 1.0293 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3370 | 3772 | 0.8935 | 0.8402 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3553 | 3643 | 0.9756 | 0.9625 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3517 | 3772 | 0.9325 | 0.8993 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3550 | 3643 | 0.9755 | 0.9641 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3128 | 3772 | 0.8295 | 0.7419 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3037 | 3643 | 0.8316 | 0.7312 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2433 | 3772 | 0.6451 | 0.4449 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2351 | 3643 | 0.6448 | 0.4257 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP5 | 72 | hr | 1476 | 1727 | 3772 | 0.4580 | 0.1218 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP6 | 72 | hr | 1476 | 1787 | 3643 | 0.4925 | 0.1603 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1472 | 3772 | 0.3901 | -0.0028 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1492 | 3643 | 0.4104 | 0.0080 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1389 | 3772 | 0.3682 | -0.0446 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1327 | 3643 | 0.3653 | -0.0788 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1447 | 3772 | 0.3837 | -0.0151 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1309 | 3643 | 0.3597 | -0.0895 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1545 | 3772 | 0.4097 | 0.0336 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1467 | 3643 | 0.4028 | -0.0068 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1345 | 3772 | 0.3566 | -0.0668 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1193 | 3643 | 0.3289 | -0.1503 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 1476 | 597 | 3772 | 0.1583 | -0.4897 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 1476 | 688 | 3643 | 0.1889 | -0.4449 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4029 | 3772 | 1.0681 | 1.0994 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3684 | 3772 | 0.9769 | 0.9657 |