LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | A443654 | 10 | uM | LJP6 | 72 | hr | 1476 | 988 | 3643 | 0.2709 | -0.2683 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4098 | 3772 | 1.0864 | 1.1265 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4225 | 3772 | 1.1202 | 1.1751 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4221 | 3772 | 1.1191 | 1.1731 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4251 | 3772 | 1.1270 | 1.1846 |
| SK-BR-3 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 4121 | 3772 | 1.0927 | 1.1356 |
| SK-BR-3 | SB590885 | 10 | uM | LJP5 | 72 | hr | 1476 | 1132 | 3772 | 0.3003 | -0.1797 |
| SK-BR-3 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2191 | 3643 | 0.6016 | 0.3526 |
| SK-BR-3 | Pictilisib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2106 | 3643 | 0.5769 | 0.3078 |
| SK-BR-3 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1829 | 3643 | 0.5023 | 0.1772 |
| SK-BR-3 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1808 | 3643 | 0.4956 | 0.1641 |
| SK-BR-3 | Pictilisib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1669 | 3643 | 0.4590 | 0.0987 |
| SK-BR-3 | Pictilisib | 10 | uM | LJP6 | 72 | hr | 1476 | 1499 | 3643 | 0.4120 | 0.0109 |
| SK-BR-3 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4125 | 3772 | 1.0940 | 1.1375 |
| SK-BR-3 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3786 | 3772 | 1.0034 | 1.0038 |
| SK-BR-3 | PD184352 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3824 | 3772 | 1.0137 | 1.0195 |
| SK-BR-3 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3824 | 3772 | 1.0136 | 1.0196 |
| SK-BR-3 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3597 | 3772 | 0.9537 | 0.9311 |
| SK-BR-3 | PD184352 | 10 | uM | LJP5 | 72 | hr | 1476 | 2732 | 3772 | 0.7243 | 0.5755 |
| SK-BR-3 | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3715 | 3772 | 0.9852 | 0.9777 |
| SK-BR-3 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3725 | 3772 | 0.9874 | 0.9807 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4215 | 3772 | 1.1174 | 1.1702 |
| SK-BR-3 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3989 | 3772 | 1.0579 | 1.0846 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2775 | 3772 | 0.7359 | 0.5934 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 72 | hr | 1476 | 2004 | 3772 | 0.5313 | 0.2519 |