LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GSK1059615 | 10 | uM | LJP5 | 72 | hr | 1476 | 757 | 3772 | 0.2010 | -0.3905 |
| SK-BR-3 | GSK1059615 | 10 | uM | LJP6 | 72 | hr | 1476 | 843 | 3643 | 0.2315 | -0.3515 |
| SK-BR-3 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3080 | 3772 | 0.8167 | 0.7220 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2912 | 3772 | 0.7722 | 0.6521 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3015 | 3772 | 0.7997 | 0.6954 |
| SK-BR-3 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3169 | 3772 | 0.8404 | 0.7588 |
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3159 | 3772 | 0.8374 | 0.7540 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 72 | hr | 1476 | 3133 | 3772 | 0.8307 | 0.7433 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2843 | 3643 | 0.7834 | 0.6610 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2808 | 3643 | 0.7738 | 0.6452 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2945 | 3643 | 0.8090 | 0.6995 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2894 | 3643 | 0.7970 | 0.6825 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2867 | 3643 | 0.7874 | 0.6641 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 72 | hr | 1476 | 2245 | 3643 | 0.6191 | 0.3848 |
| SK-BR-3 | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4036 | 3643 | 1.1062 | 1.1581 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3871 | 3643 | 1.0612 | 1.0910 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3937 | 3643 | 1.0790 | 1.1174 |
| SK-BR-3 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4083 | 3643 | 1.1209 | 1.1841 |
| SK-BR-3 | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 4062 | 3643 | 1.1133 | 1.1693 |
| SK-BR-3 | Linifanib | 10 | uM | LJP6 | 72 | hr | 1476 | 1846 | 3643 | 0.5070 | 0.1857 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4081 | 3772 | 1.0818 | 1.1193 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4097 | 3772 | 1.0861 | 1.1255 |
| SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3923 | 3772 | 1.0402 | 1.0591 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3752 | 3772 | 0.9946 | 0.9916 |
| SK-BR-3 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2696 | 3772 | 0.7147 | 0.5600 |