LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1621 | 3772 | 0.4299 | 0.0715 |
| SK-BR-3 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1655 | 3772 | 0.4388 | 0.0878 |
| SK-BR-3 | Luminespib | 10 | uM | LJP5 | 72 | hr | 1476 | 1525 | 3772 | 0.4044 | 0.0241 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2449 | 3772 | 0.6495 | 0.4534 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2842 | 3772 | 0.7535 | 0.6225 |
| SK-BR-3 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2930 | 3772 | 0.7768 | 0.6594 |
| SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3079 | 3772 | 0.8162 | 0.7211 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3127 | 3772 | 0.8293 | 0.7416 |
| SK-BR-3 | AZD8330 | 10 | uM | LJP5 | 72 | hr | 1476 | 3188 | 3772 | 0.8456 | 0.7667 |
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2940 | 3772 | 0.7796 | 0.6634 |
| SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3134 | 3772 | 0.8309 | 0.7437 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3457 | 3772 | 0.9169 | 0.8751 |
| SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3584 | 3772 | 0.9502 | 0.9259 |
| SK-BR-3 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3644 | 3772 | 0.9660 | 0.9484 |
| SK-BR-3 | TGX221 | 10 | uM | LJP5 | 72 | hr | 1476 | 3452 | 3772 | 0.9149 | 0.8716 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3955 | 3772 | 1.0483 | 1.0699 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3496 | 3643 | 0.9597 | 0.9373 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3675 | 3772 | 0.9745 | 0.9623 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2965 | 3643 | 0.8150 | 0.7098 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2676 | 3772 | 0.7096 | 0.5515 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2285 | 3643 | 0.6277 | 0.3978 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1535 | 3772 | 0.4068 | 0.0284 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1490 | 3643 | 0.4095 | 0.0064 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1010 | 3772 | 0.2677 | -0.2457 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1137 | 3643 | 0.3128 | -0.1825 |