LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3575 | 3643 | 0.9836 | 0.9780 |
| SK-BR-3 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3201 | 3643 | 0.8802 | 0.8148 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2580 | 3643 | 0.7096 | 0.5372 |
| SK-BR-3 | Nintedanib | 10 | uM | LJP6 | 72 | hr | 1476 | 977 | 3643 | 0.2676 | -0.2751 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3955 | 3772 | 1.0486 | 1.0715 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2627 | 3772 | 0.6966 | 0.5308 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1525 | 3772 | 0.4045 | 0.0241 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1376 | 3772 | 0.3650 | -0.0507 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1454 | 3772 | 0.3857 | -0.0110 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 72 | hr | 1476 | 1382 | 3772 | 0.3667 | -0.0474 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3484 | 3643 | 0.9559 | 0.9311 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2832 | 3643 | 0.7753 | 0.6401 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1940 | 3643 | 0.5322 | 0.2302 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1387 | 3643 | 0.3798 | -0.0516 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1083 | 3643 | 0.2978 | -0.2125 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1476 | 807 | 3643 | 0.2211 | -0.3737 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3025 | 3772 | 0.8021 | 0.6992 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2188 | 3772 | 0.5802 | 0.3374 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1478 | 3772 | 0.3918 | 0.0004 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1500 | 3772 | 0.3980 | 0.0120 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1634 | 3772 | 0.4332 | 0.0774 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 72 | hr | 1476 | 1088 | 3772 | 0.2886 | -0.2019 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1618 | 3772 | 0.4290 | 0.0699 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1650 | 3772 | 0.4376 | 0.0857 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1731 | 3772 | 0.4589 | 0.1246 |