LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1592 | 3643 | 0.4375 | 0.0585 |
| SK-BR-3 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 1476 | 1220 | 3643 | 0.3365 | -0.1353 |
| SK-BR-3 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2440 | 3643 | 0.6716 | 0.4737 |
| SK-BR-3 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1912 | 3643 | 0.5273 | 0.2232 |
| SK-BR-3 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1403 | 3643 | 0.3864 | -0.0378 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1164 | 3643 | 0.3202 | -0.1673 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 931 | 3643 | 0.2563 | -0.2989 |
| SK-BR-3 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 1476 | 659 | 3643 | 0.1810 | -0.4631 |
| SK-BR-3 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1523 | 3643 | 0.4188 | 0.0238 |
| SK-BR-3 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1536 | 3643 | 0.4232 | 0.0322 |
| SK-BR-3 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1427 | 3643 | 0.3929 | -0.0252 |
| SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1335 | 3643 | 0.3677 | -0.0739 |
| SK-BR-3 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1192 | 3643 | 0.3288 | -0.1507 |
| SK-BR-3 | Torin1 | 10 | uM | LJP6 | 72 | hr | 1476 | 1116 | 3643 | 0.3079 | -0.1929 |
| SK-BR-3 | Torin2 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1310 | 3772 | 0.3474 | -0.0852 |
| SK-BR-3 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1289 | 3772 | 0.3420 | -0.0952 |
| SK-BR-3 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1255 | 3772 | 0.3327 | -0.1136 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1307 | 3772 | 0.3468 | -0.0859 |
| SK-BR-3 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1143 | 3772 | 0.3033 | -0.1722 |
| SK-BR-3 | Torin2 | 10 | uM | LJP5 | 72 | hr | 1476 | 1128 | 3772 | 0.2990 | -0.1806 |
| SK-BR-3 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2226 | 3643 | 0.6117 | 0.3704 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2255 | 3643 | 0.6198 | 0.3842 |
| SK-BR-3 | WZ-4-145 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2062 | 3643 | 0.5665 | 0.2916 |
| SK-BR-3 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1911 | 3643 | 0.5242 | 0.2158 |
| SK-BR-3 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1718 | 3643 | 0.4706 | 0.1186 |