LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 72
hr
 1235 4527 4513 1.0031 1.0043
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 72
hr
 1235 4126 4513 0.9141 0.8817
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 72
hr
 1235 3949 4513 0.8750 0.8278
MDA-MB-231 Omipalisib
0.12
uM
LJP6
 72
hr
 1235 1518 4513 0.3365 0.0863
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 72
hr
 1235 4227 4513 0.9366 0.9128
MDA-MB-231 GW843682X
0.12
uM
LJP6
 72
hr
 1235 3093 4513 0.6853 0.5666
MDA-MB-231 HG-5-113-01
0.12
uM
LJP5
 72
hr
 1235 4463 4513 0.9889 0.9848
MDA-MB-231 HG-5-88-01
0.12
uM
LJP6
 72
hr
 1235 4271 4513 0.9463 0.9261
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 1235 4326 4513 0.9584 0.9428
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 72
hr
 1235 3525 4513 0.7811 0.6986
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1235 4098 4513 0.9080 0.8733
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 72
hr
 1235 4135 4513 0.9162 0.8846
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 72
hr
 1235 4154 4513 0.9205 0.8905
MDA-MB-231 Linifanib
0.12
uM
LJP6
 72
hr
 1235 4721 4513 1.0460 1.0634
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 72
hr
 1235 3882 4513 0.8601 0.8074
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1235 959 4513 0.2125 -0.0845
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1235 916 4513 0.2030 -0.0975
MDA-MB-231 MK2206
0.12
uM
LJP6
 72
hr
 1235 3998 4513 0.8858 0.8428
MDA-MB-231 Neratinib
0.12
uM
LJP5
 72
hr
 1235 4531 4513 1.0040 1.0055
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 72
hr
 1235 4416 4513 0.9784 0.9703
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 72
hr
 1235 4658 4513 1.0321 1.0442
MDA-MB-231 NU7441
0.12
uM
LJP5
 72
hr
 1235 4631 4513 1.0261 1.0359
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 72
hr
 1235 1470 4513 0.3258 0.0715
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 72
hr
 1235 3542 4513 0.7847 0.7036
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 72
hr
 1235 2570 4513 0.5695 0.4072