LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 1235 3493 4513 0.7740 0.6887
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 72
hr
 1235 1357 4513 0.3008 0.0371
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 1235 4196 4513 0.9297 0.9032
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 72
hr
 1235 4457 4513 0.9875 0.9828
MDA-MB-231 BX-912
0.12
uM
LJP5
 72
hr
 1235 3850 4513 0.8530 0.7975
MDA-MB-231 Canertinib
0.12
uM
LJP6
 72
hr
 1235 4322 4513 0.9577 0.9417
MDA-MB-231 Celastrol
0.12
uM
LJP6
 72
hr
 1235 4729 4513 1.0477 1.0657
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 1235 773 4513 0.1713 -0.1411
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1235 506 4513 0.1121 -0.2227
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 1235 3769 4513 0.8351 0.7729
MDA-MB-231 CP724714
0.12
uM
LJP5
 72
hr
 1235 4689 4513 1.0390 1.0537
MDA-MB-231 CP466722
0.12
uM
LJP5
 72
hr
 1235 4537 4513 1.0052 1.0071
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 72
hr
 1235 4475 4513 0.9915 0.9883
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 72
hr
 1235 3565 4513 0.7900 0.7108
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 72
hr
 1235 1345 4513 0.2981 0.0335
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 72
hr
 1235 801 4513 0.1775 -0.1326
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 72
hr
 1235 3912 4513 0.8668 0.8166
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 72
hr
 1235 4878 4513 1.0808 1.1113
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 72
hr
 1235 4277 4513 0.9476 0.9278
MDA-MB-231 Foretinib
0.12
uM
LJP5
 72
hr
 1235 3081 4513 0.6828 0.5631
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 1235 4308 4513 0.9544 0.9373
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 72
hr
 1235 3713 4513 0.8228 0.7559
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 72
hr
 1235 4265 4513 0.9450 0.9242
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 72
hr
 1235 1210 4513 0.2681 -0.0079
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 72
hr
 1235 1101 4513 0.2439 -0.0412