LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1478 | 4093 | 0.3613 | 0.0933 |
| MCF7 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 617 | 4093 | 0.1508 | -0.2054 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 388 | 4093 | 0.0949 | -0.2848 |
| MCF7 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 2370 | 4093 | 0.5791 | 0.4026 |
| MCF7 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1468 | 4093 | 0.3588 | 0.0899 |
| MCF7 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 777 | 4093 | 0.1900 | -0.1498 |
| MCF7 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 503 | 4093 | 0.1230 | -0.2449 |
| MCF7 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 694 | 4093 | 0.1696 | -0.1788 |
| MCF7 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1083 | 4093 | 0.2647 | -0.0438 |
| MCF7 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 893 | 4093 | 0.2183 | -0.1097 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 409 | 4093 | 0.0999 | -0.2776 |
| MCF7 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1189 | 4093 | 0.2907 | -0.0069 |
| MCF7 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1613 | 4093 | 0.3943 | 0.1402 |
| MCF7 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1130 | 4093 | 0.2762 | -0.0275 |
| MCF7 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1189 | 4093 | 0.2907 | -0.0069 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 403 | 4093 | 0.0985 | -0.2797 |
| MCF7 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1255 | 4093 | 0.3068 | 0.0160 |
| MCF7 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1830 | 4093 | 0.4473 | 0.2154 |
| MCF7 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 170 | 4093 | 0.0415 | -0.3605 |
| MCF7 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 851 | 4093 | 0.2079 | -0.1244 |
| MCF7 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 772 | 4093 | 0.1887 | -0.1516 |
| MCF7 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 685 | 4093 | 0.1675 | -0.1817 |
| MCF7 | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 3821 | 4093 | 0.9336 | 0.9057 |
| MCF7 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 854 | 4093 | 0.2087 | -0.1232 |
| MCF7 | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1186 | 4093 | 0.2898 | -0.0082 |