LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4044 | 4093 | 0.9882 | 0.9832 |
| MCF7 | Torin1 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1313 | 4093 | 0.3208 | 0.0359 |
| MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 997 | 4093 | 0.2438 | -0.0735 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1406 | 4093 | 0.3436 | 0.0682 |
| MCF7 | Trametinib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 2084 | 4093 | 0.5093 | 0.3035 |
| MCF7 | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4462 | 4093 | 1.0903 | 1.1282 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 4347 | 4093 | 1.0622 | 1.0883 |
| MCF7 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1706 | 4093 | 0.4170 | 0.1724 |
| MCF7 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1696 | 4093 | 0.4145 | 0.1688 |
| MCF7 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1318 | 4093 | 0.3220 | 0.0376 |
| MCF7 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 665 | 4093 | 0.1626 | -0.1886 |
| MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 2703 | 4093 | 0.6605 | 0.5181 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 4177 | 4093 | 1.0207 | 1.0294 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 3484 | 4093 | 0.8514 | 0.7890 |
| MCF7 | ZSTK474 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1396 | 4093 | 0.3412 | 0.0649 |
| MCF7 | Afatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2817 | 4093 | 0.6883 | 0.5575 |
| MCF7 | Sigma A6730 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2347 | 4093 | 0.5735 | 0.3946 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 652 | 4093 | 0.1593 | -0.1934 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 591 | 4093 | 0.1445 | -0.2144 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 768 | 4093 | 0.1877 | -0.1530 |
| MCF7 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3734 | 4093 | 0.9125 | 0.8757 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1184 | 4093 | 0.2893 | -0.0089 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1024 | 4093 | 0.2502 | -0.0644 |
| MCF7 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2091 | 4093 | 0.5110 | 0.3059 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1417 | 4093 | 0.3462 | 0.0719 |