LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 PD0325901
0.37
uM
LJP5
 72
hr
 1209 2390 4093 0.5839 0.4094
MCF7 PD0325901
0.37
uM
LJP6
 72
hr
 1209 2523 4093 0.6164 0.4555
MCF7 PD173074
0.37
uM
LJP6
 72
hr
 1209 3920 4093 0.9579 0.9402
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1209 2969 4093 0.7256 0.6104
MCF7 Pelitinib
0.37
uM
LJP5
 72
hr
 1209 3818 4093 0.9329 0.9047
MCF7 PF431396
0.37
uM
LJP5
 72
hr
 1209 1470 4093 0.3592 0.0904
MCF7 PF477736
0.37
uM
LJP5
 72
hr
 1209 1945 4093 0.4753 0.2552
MCF7 PF562271
0.37
uM
LJP6
 72
hr
 1209 2452 4093 0.5992 0.4311
MCF7 PHA-665752
0.37
uM
LJP5
 72
hr
 1209 4159 4093 1.0162 1.0230
MCF7 PHA-793887
0.37
uM
LJP6
 72
hr
 1209 1226 4093 0.2997 0.0059
MCF7 PI103
0.37
uM
LJP6
 72
hr
 1209 1171 4093 0.2863 -0.0131
MCF7 PLX-4720
0.37
uM
LJP5
 72
hr
 1209 4295 4093 1.0494 1.0701
MCF7 QL-X-138
0.37
uM
LJP6
 72
hr
 1209 1937 4093 0.4733 0.2523
MCF7 QL-XII-47
0.37
uM
LJP6
 72
hr
 1209 1317 4093 0.3219 0.0374
MCF7 Radicicol
0.37
uM
LJP5
 72
hr
 1209 1564 4093 0.3822 0.1230
MCF7 Radicicol
0.37
uM
LJP6
 72
hr
 1209 1432 4093 0.3500 0.0774
MCF7 Seliciclib
0.37
uM
LJP5
 72
hr
 1209 3931 4093 0.9606 0.9441
MCF7 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1209 4219 4093 1.0309 1.0439
MCF7 XL147
0.37
uM
LJP5
 72
hr
 1209 4269 4093 1.0431 1.0612
MCF7 Saracatinib
0.37
uM
LJP6
 72
hr
 1209 2897 4093 0.7079 0.5853
MCF7 Selumetinib
0.37
uM
LJP6
 72
hr
 1209 2499 4093 0.6106 0.4473
MCF7 Sirolimus
0.37
uM
LJP6
 72
hr
 1209 2249 4093 0.5496 0.3607
MCF7 Sorafenib
0.37
uM
LJP6
 72
hr
 1209 3825 4093 0.9347 0.9073
MCF7 SU11274
0.37
uM
LJP5
 72
hr
 1209 3974 4093 0.9710 0.9589
MCF7 Fedratinib
0.37
uM
LJP5
 72
hr
 1209 3198 4093 0.7814 0.6897