LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 GW843682X
0.04
uM
LJP6
 72
hr
 1209 2523 4093 0.6166 0.4557
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1209 3957 4093 0.9668 0.9528
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1209 3074 4093 0.7510 0.6466
MCF7 Imatinib
0.04
uM
LJP6
 72
hr
 1209 3887 4093 0.9498 0.9288
MCF7 JNK-9L
0.04
uM
LJP6
 72
hr
 1209 3341 4093 0.8164 0.7394
MCF7 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1209 2904 4093 0.7097 0.5879
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1209 3516 4093 0.8591 0.8000
MCF7 LDN-193189
0.04
uM
LJP5
 72
hr
 1209 4394 4093 1.0737 1.1046
MCF7 Linifanib
0.04
uM
LJP6
 72
hr
 1209 4004 4093 0.9784 0.9694
MCF7 Linsitinib
0.04
uM
LJP5
 72
hr
 1209 3271 4093 0.7992 0.7149
MCF7 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1209 1239 4093 0.3029 0.0104
MCF7 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1209 1258 4093 0.3074 0.0168
MCF7 MK2206
0.04
uM
LJP6
 72
hr
 1209 2425 4093 0.5925 0.4215
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1209 3690 4093 0.9017 0.8605
MCF7 Nilotinib
0.04
uM
LJP5
 72
hr
 1209 4224 4093 1.0321 1.0455
MCF7 Nintedanib
0.04
uM
LJP6
 72
hr
 1209 4173 4093 1.0197 1.0280
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1209 4014 4093 0.9807 0.9726
MCF7 Dactolisib
0.04
uM
LJP5
 72
hr
 1209 1186 4093 0.2899 -0.0079
MCF7 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1209 1984 4093 0.4848 0.2687
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1209 2761 4093 0.6746 0.5381
MCF7 PD0325901
0.04
uM
LJP5
 72
hr
 1209 2624 4093 0.6412 0.4907
MCF7 PD0325901
0.04
uM
LJP6
 72
hr
 1209 2638 4093 0.6446 0.4955
MCF7 PD173074
0.04
uM
LJP6
 72
hr
 1209 4081 4093 0.9972 0.9961
MCF7 PD184352
0.04
uM
LJP5
 72
hr
 1209 3272 4093 0.7996 0.7155
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1209 4399 4093 1.0748 1.1061