LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 2748 | 4093 | 0.6716 | 0.5338 |
| MCF7 | Sirolimus | 3.33 | uM | LJP6 | 72 | hr | 1209 | 2273 | 4093 | 0.5553 | 0.3688 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3843 | 4093 | 0.9391 | 0.9135 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3108 | 4093 | 0.7594 | 0.6585 |
| MCF7 | Fedratinib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1391 | 4093 | 0.3399 | 0.0630 |
| MCF7 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 4072 | 4093 | 0.9950 | 0.9928 |
| MCF7 | Torin1 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1158 | 4093 | 0.2830 | -0.0178 |
| MCF7 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1060 | 4093 | 0.2590 | -0.0519 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1426 | 4093 | 0.3484 | 0.0751 |
| MCF7 | Trametinib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 2307 | 4093 | 0.5638 | 0.3808 |
| MCF7 | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 2957 | 4093 | 0.7226 | 0.6063 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 4259 | 4093 | 1.0406 | 1.0577 |
| MCF7 | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 1209 | 527 | 4093 | 0.1289 | -0.2365 |
| MCF7 | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 1209 | 571 | 4093 | 0.1396 | -0.2213 |
| MCF7 | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1170 | 4093 | 0.2859 | -0.0137 |
| MCF7 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 663 | 4093 | 0.1622 | -0.1893 |
| MCF7 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1687 | 4093 | 0.4123 | 0.1658 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3292 | 4093 | 0.8045 | 0.7224 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1757 | 4093 | 0.4294 | 0.1900 |
| MCF7 | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 1057 | 4093 | 0.2584 | -0.0527 |
| MCF7 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 922 | 4093 | 0.2254 | -0.0995 |
| MCF7 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 830 | 4093 | 0.2029 | -0.1315 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 679 | 4093 | 0.1660 | -0.1839 |
| MCF7 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 443 | 4093 | 0.1084 | -0.2656 |
| MCF7 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 697 | 4093 | 0.1704 | -0.1776 |