LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 1235 4078 4513 0.9036 0.8673
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 1235 4466 4513 0.9895 0.9856
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 1235 517 4513 0.1145 -0.2194
MDA-MB-231 AT-7519
0.12
uM
LJP6
 72
hr
 1235 947 4513 0.2099 -0.0881
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 72
hr
 1235 2782 4513 0.6164 0.4717
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 72
hr
 1235 4131 4513 0.9154 0.8835
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 1235 2007 4513 0.4447 0.2353
MDA-MB-231 AZD8055
0.12
uM
LJP6
 72
hr
 1235 2180 4513 0.4830 0.2880
MDA-MB-231 AZD8330
0.12
uM
LJP5
 72
hr
 1235 1310 4513 0.2902 0.0226
MDA-MB-231 Barasertib
0.12
uM
LJP5
 72
hr
 1235 1523 4513 0.3376 0.0878
MDA-MB-231 BI-2536
0.12
uM
LJP6
 72
hr
 1235 1054 4513 0.2337 -0.0553
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 1235 3792 4513 0.8402 0.7799
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 1235 554 4513 0.1227 -0.2081
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 72
hr
 1235 2564 4513 0.5681 0.4053
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1235 4801 4513 1.0637 1.0877
MDA-MB-231 SB590885
0.12
uM
LJP5
 72
hr
 1235 4334 4513 0.9603 0.9453
MDA-MB-231 PIK-93
0.12
uM
LJP5
 72
hr
 1235 4427 4513 0.9808 0.9736
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 1235 3477 4513 0.7704 0.6838
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 72
hr
 1235 4439 4513 0.9835 0.9773
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 1235 842 4513 0.1866 -0.1201
MDA-MB-231 A443654
0.12
uM
LJP6
 72
hr
 1235 2124 4513 0.4706 0.2709
MDA-MB-231 OSI-027
0.12
uM
LJP6
 72
hr
 1235 4078 4513 0.9035 0.8671
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 72
hr
 1235 4028 4513 0.8925 0.8519
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1235 3420 4513 0.7579 0.6665
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 1235 3320 4513 0.7356 0.6358