LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 1235 4715 4513 1.0447 1.0615
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 72
hr
 1235 4659 4513 1.0323 1.0444
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1235 4156 4513 0.9208 0.8910
MDA-MB-231 XL147
0.04
uM
LJP5
 72
hr
 1235 5018 4513 1.1119 1.1541
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 72
hr
 1235 3593 4513 0.7961 0.7192
MDA-MB-231 Selumetinib
0.04
uM
LJP6
 72
hr
 1235 3888 4513 0.8614 0.8091
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 1235 3461 4513 0.7668 0.6789
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 72
hr
 1235 4652 4513 1.0308 1.0424
MDA-MB-231 SU11274
0.04
uM
LJP5
 72
hr
 1235 4689 4513 1.0389 1.0535
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 72
hr
 1235 4389 4513 0.9725 0.9622
MDA-MB-231 TGX221
0.04
uM
LJP5
 72
hr
 1235 3959 4513 0.8772 0.8309
MDA-MB-231 Torin1
0.04
uM
LJP6
 72
hr
 1235 2359 4513 0.5226 0.3426
MDA-MB-231 Torin2
0.04
uM
LJP5
 72
hr
 1235 1584 4513 0.3511 0.1064
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 72
hr
 1235 1382 4513 0.3063 0.0447
MDA-MB-231 Trametinib
0.04
uM
LJP5
 72
hr
 1235 1343 4513 0.2975 0.0327
MDA-MB-231 TWS119
0.04
uM
LJP5
 72
hr
 1235 4320 4513 0.9573 0.9411
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4745 4513 1.0513 1.0707
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 72
hr
 1235 4860 4513 1.0767 1.1057
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 72
hr
 1235 4613 4513 1.0221 1.0304
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 1235 2048 4513 0.4538 0.2479
MDA-MB-231 WZ3105
0.04
uM
LJP5
 72
hr
 1235 498 4513 0.1103 -0.2251
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 72
hr
 1235 3862 4513 0.8557 0.8013
MDA-MB-231 Y39983
0.04
uM
LJP6
 72
hr
 1235 3398 4513 0.7529 0.6597
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4673 4513 1.0355 1.0488
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 72
hr
 1235 3680 4513 0.8155 0.7459