LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1235 1037 4513 0.2298 -0.0607
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1235 975 4513 0.2161 -0.0795
MDA-MB-231 MK2206
0.04
uM
LJP6
 72
hr
 1235 4100 4513 0.9084 0.8738
MDA-MB-231 Neratinib
0.04
uM
LJP5
 72
hr
 1235 4700 4513 1.0414 1.0570
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 72
hr
 1235 4444 4513 0.9847 0.9790
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 72
hr
 1235 4845 4513 1.0734 1.1011
MDA-MB-231 NU7441
0.04
uM
LJP5
 72
hr
 1235 4817 4513 1.0674 1.0928
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 72
hr
 1235 1676 4513 0.3714 0.1344
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1235 3892 4513 0.8623 0.8103
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 72
hr
 1235 2837 4513 0.6286 0.4886
MDA-MB-231 PD0325901
0.04
uM
LJP5
 72
hr
 1235 3358 4513 0.7440 0.6474
MDA-MB-231 PD0325901
0.04
uM
LJP6
 72
hr
 1235 2984 4513 0.6612 0.5334
MDA-MB-231 PD173074
0.04
uM
LJP6
 72
hr
 1235 4661 4513 1.0327 1.0451
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 1235 4379 4513 0.9702 0.9590
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 72
hr
 1235 4770 4513 1.0569 1.0783
MDA-MB-231 PF431396
0.04
uM
LJP5
 72
hr
 1235 4058 4513 0.8991 0.8611
MDA-MB-231 PF477736
0.04
uM
LJP5
 72
hr
 1235 4350 4513 0.9639 0.9503
MDA-MB-231 PF562271
0.04
uM
LJP6
 72
hr
 1235 3875 4513 0.8587 0.8054
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 72
hr
 1235 4901 4513 1.0860 1.1184
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 72
hr
 1235 2392 4513 0.5301 0.3529
MDA-MB-231 PI103
0.04
uM
LJP6
 72
hr
 1235 3222 4513 0.7140 0.6061
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 1235 4328 4513 0.9590 0.9436
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 72
hr
 1235 4105 4513 0.9096 0.8755
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 72
hr
 1235 2742 4513 0.6076 0.4597
MDA-MB-231 Radicicol
0.04
uM
LJP5
 72
hr
 1235 4718 4513 1.0453 1.0623