LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 R406
3.33
uM
LJP6
 72
hr
 1209 3367 4093 0.8227 0.7483
MCF7 Pictilisib
3.33
uM
LJP6
 72
hr
 1209 1112 4093 0.2717 -0.0338
MCF7 Gefitinib
3.33
uM
LJP6
 72
hr
 1209 3922 4093 0.9584 0.9409
MCF7 Geldanamycin
3.33
uM
LJP5
 72
hr
 1209 1071 4093 0.2618 -0.0478
MCF7 Geldanamycin
3.33
uM
LJP6
 72
hr
 1209 1126 4093 0.2752 -0.0289
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1209 1029 4093 0.2516 -0.0624
MCF7 GSK1059615
3.33
uM
LJP6
 72
hr
 1209 986 4093 0.2410 -0.0774
MCF7 GSK1904529A
3.33
uM
LJP6
 72
hr
 1209 1999 4093 0.4884 0.2738
MCF7 Omipalisib
3.33
uM
LJP6
 72
hr
 1209 1073 4093 0.2622 -0.0472
MCF7 GSK 690693
3.33
uM
LJP5
 72
hr
 1209 1828 4093 0.4466 0.2145
MCF7 GW843682X
3.33
uM
LJP6
 72
hr
 1209 1310 4093 0.3201 0.0348
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1209 1316 4093 0.3215 0.0369
MCF7 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1209 1982 4093 0.4843 0.2680
MCF7 Imatinib
3.33
uM
LJP6
 72
hr
 1209 3840 4093 0.9382 0.9123
MCF7 JNK-9L
3.33
uM
LJP6
 72
hr
 1209 353 4093 0.0862 -0.2971
MCF7 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1209 1326 4093 0.3241 0.0405
MCF7 Lapatinib
3.33
uM
LJP6
 72
hr
 1209 3577 4093 0.8740 0.8212
MCF7 LDN-193189
3.33
uM
LJP5
 72
hr
 1209 967 4093 0.2363 -0.0841
MCF7 Linifanib
3.33
uM
LJP6
 72
hr
 1209 3423 4093 0.8365 0.7679
MCF7 Linsitinib
3.33
uM
LJP5
 72
hr
 1209 1932 4093 0.4720 0.2506
MCF7 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1209 530 4093 0.1296 -0.2356
MCF7 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1209 499 4093 0.1219 -0.2464
MCF7 MK2206
3.33
uM
LJP6
 72
hr
 1209 1618 4093 0.3953 0.1417
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1209 1390 4093 0.3396 0.0626
MCF7 Nilotinib
3.33
uM
LJP5
 72
hr
 1209 3829 4093 0.9357 0.9087