LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PI103
0.37
uM
LJP6
 72
hr
 1235 1617 4513 0.3583 0.1164
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 1235 4537 4513 1.0053 1.0073
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 72
hr
 1235 3389 4513 0.7510 0.6571
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 72
hr
 1235 1785 4513 0.3955 0.1676
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 1235 1705 4513 0.3778 0.1432
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1235 1539 4513 0.3410 0.0925
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 72
hr
 1235 4369 4513 0.9680 0.9559
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1235 4096 4513 0.9075 0.8726
MDA-MB-231 XL147
0.37
uM
LJP5
 72
hr
 1235 4822 4513 1.0683 1.0941
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 1235 2933 4513 0.6500 0.5180
MDA-MB-231 Selumetinib
0.37
uM
LJP6
 72
hr
 1235 3086 4513 0.6837 0.5644
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 1235 3473 4513 0.7695 0.6825
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 72
hr
 1235 4437 4513 0.9830 0.9766
MDA-MB-231 SU11274
0.37
uM
LJP5
 72
hr
 1235 4429 4513 0.9813 0.9742
MDA-MB-231 Fedratinib
0.37
uM
LJP5
 72
hr
 1235 3655 4513 0.8099 0.7382
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 1235 4099 4513 0.9082 0.8736
MDA-MB-231 Torin1
0.37
uM
LJP6
 72
hr
 1235 1650 4513 0.3657 0.1265
MDA-MB-231 Torin2
0.37
uM
LJP5
 72
hr
 1235 1087 4513 0.2408 -0.0454
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 1235 1444 4513 0.3199 0.0635
MDA-MB-231 Trametinib
0.37
uM
LJP5
 72
hr
 1235 1329 4513 0.2945 0.0285
MDA-MB-231 TWS119
0.37
uM
LJP5
 72
hr
 1235 4018 4513 0.8903 0.8489
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 72
hr
 1235 4614 4513 1.0222 1.0306
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 1235 2841 4513 0.6294 0.4897
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 1235 2493 4513 0.5525 0.3837
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 72
hr
 1235 1597 4513 0.3539 0.1103