LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 TWS119
3.33
uM
LJP5
 72
hr
 1235 3040 4513 0.6737 0.5506
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 72
hr
 1235 4224 4513 0.9360 0.9118
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 1235 858 4513 0.1902 -0.1151
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1235 898 4513 0.1990 -0.1031
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 72
hr
 1235 1552 4513 0.3439 0.0964
MDA-MB-231 WZ3105
3.33
uM
LJP5
 72
hr
 1235 518 4513 0.1148 -0.2189
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 72
hr
 1235 1616 4513 0.3582 0.1162
MDA-MB-231 Y39983
3.33
uM
LJP6
 72
hr
 1235 2849 4513 0.6314 0.4923
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 1235 2698 4513 0.5979 0.4463
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 72
hr
 1235 2374 4513 0.5260 0.3473
MDA-MB-231 Afatinib
10.0
uM
LJP6
 72
hr
 1235 628 4513 0.1393 -0.1853
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 72
hr
 1235 2695 4513 0.5972 0.4453
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 72
hr
 1235 414 4513 0.0918 -0.2507
MDA-MB-231 AT-7519
10.0
uM
LJP6
 72
hr
 1235 259 4513 0.0575 -0.2979
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 72
hr
 1235 361 4513 0.0800 -0.2669
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 72
hr
 1235 3063 4513 0.6787 0.5575
MDA-MB-231 AZD7762
10.0
uM
LJP6
 72
hr
 1235 409 4513 0.0907 -0.2522
MDA-MB-231 AZD8055
10.0
uM
LJP6
 72
hr
 1235 562 4513 0.1246 -0.2055
MDA-MB-231 AZD8330
10.0
uM
LJP5
 72
hr
 1235 1448 4513 0.3208 0.0647
MDA-MB-231 Barasertib
10.0
uM
LJP5
 72
hr
 1235 1397 4513 0.3097 0.0493
MDA-MB-231 BI-2536
10.0
uM
LJP6
 72
hr
 1235 617 4513 0.1368 -0.1886
MDA-MB-231 BMS345541
10.0
uM
LJP6
 72
hr
 1235 408 4513 0.0905 -0.2524
MDA-MB-231 SNS-032
10.0
uM
LJP6
 72
hr
 1235 590 4513 0.1308 -0.1970
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 72
hr
 1235 1280 4513 0.2837 0.0136
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 72
hr
 1235 1349 4513 0.2990 0.0347