LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 PF431396
3.33
uM
LJP5
 72
hr
 1235 1271 4513 0.2817 0.0109
MDA-MB-231 PF477736
3.33
uM
LJP5
 72
hr
 1235 1498 4513 0.3320 0.0802
MDA-MB-231 PF562271
3.33
uM
LJP6
 72
hr
 1235 1258 4513 0.2787 0.0067
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 72
hr
 1235 4343 4513 0.9623 0.9481
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 72
hr
 1235 690 4513 0.1529 -0.1665
MDA-MB-231 PI103
3.33
uM
LJP6
 72
hr
 1235 1612 4513 0.3571 0.1147
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 72
hr
 1235 4064 4513 0.9004 0.8628
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 72
hr
 1235 2125 4513 0.4708 0.2712
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 72
hr
 1235 997 4513 0.2209 -0.0729
MDA-MB-231 Radicicol
3.33
uM
LJP5
 72
hr
 1235 916 4513 0.2031 -0.0974
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 1235 1072 4513 0.2375 -0.0500
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 72
hr
 1235 3754 4513 0.8319 0.7684
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1235 4242 4513 0.9398 0.9171
MDA-MB-231 XL147
3.33
uM
LJP5
 72
hr
 1235 4806 4513 1.0648 1.0892
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 72
hr
 1235 2626 4513 0.5819 0.4243
MDA-MB-231 Selumetinib
3.33
uM
LJP6
 72
hr
 1235 2332 4513 0.5167 0.3344
MDA-MB-231 Sirolimus
3.33
uM
LJP6
 72
hr
 1235 3311 4513 0.7336 0.6332
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 72
hr
 1235 4497 4513 0.9965 0.9951
MDA-MB-231 SU11274
3.33
uM
LJP5
 72
hr
 1235 3672 4513 0.8137 0.7434
MDA-MB-231 Fedratinib
3.33
uM
LJP5
 72
hr
 1235 1103 4513 0.2444 -0.0406
MDA-MB-231 TGX221
3.33
uM
LJP5
 72
hr
 1235 4251 4513 0.9420 0.9201
MDA-MB-231 Torin1
3.33
uM
LJP6
 72
hr
 1235 1409 4513 0.3122 0.0529
MDA-MB-231 Torin2
3.33
uM
LJP5
 72
hr
 1235 428 4513 0.0948 -0.2465
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 72
hr
 1235 1421 4513 0.3148 0.0565
MDA-MB-231 Trametinib
3.33
uM
LJP5
 72
hr
 1235 1275 4513 0.2826 0.0121