LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1235 3542 4513 0.7849 0.7038
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 1235 4253 4513 0.9424 0.9207
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 72
hr
 1235 4088 4513 0.9058 0.8702
MDA-MB-231 Linifanib
0.37
uM
LJP6
 72
hr
 1235 4667 4513 1.0340 1.0468
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 72
hr
 1235 3787 4513 0.8390 0.7783
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1235 756 4513 0.1676 -0.1462
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1235 692 4513 0.1533 -0.1660
MDA-MB-231 MK2206
0.37
uM
LJP6
 72
hr
 1235 3881 4513 0.8600 0.8072
MDA-MB-231 Neratinib
0.37
uM
LJP5
 72
hr
 1235 3537 4513 0.7838 0.7022
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 72
hr
 1235 4298 4513 0.9524 0.9344
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 72
hr
 1235 4411 4513 0.9773 0.9687
MDA-MB-231 NU7441
0.37
uM
LJP5
 72
hr
 1235 4558 4513 1.0100 1.0137
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 72
hr
 1235 1191 4513 0.2640 -0.0135
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 1235 2913 4513 0.6455 0.5118
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 72
hr
 1235 2272 4513 0.5035 0.3163
MDA-MB-231 PD0325901
0.37
uM
LJP5
 72
hr
 1235 1847 4513 0.4094 0.1866
MDA-MB-231 PD0325901
0.37
uM
LJP6
 72
hr
 1235 1800 4513 0.3988 0.1721
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 1235 5078 4513 1.1252 1.1724
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 1235 3778 4513 0.8370 0.7756
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 72
hr
 1235 4219 4513 0.9349 0.9103
MDA-MB-231 PF431396
0.37
uM
LJP5
 72
hr
 1235 1914 4513 0.4242 0.2071
MDA-MB-231 PF477736
0.37
uM
LJP5
 72
hr
 1235 3065 4513 0.6791 0.5580
MDA-MB-231 PF562271
0.37
uM
LJP6
 72
hr
 1235 3116 4513 0.6905 0.5738
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 72
hr
 1235 4719 4513 1.0456 1.0628
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 72
hr
 1235 1167 4513 0.2586 -0.0209