LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 CP724714
0.37
uM
LJP5
 72
hr
 1235 4612 4513 1.0219 1.0302
MDA-MB-231 CP466722
0.37
uM
LJP5
 72
hr
 1235 3084 4513 0.6833 0.5639
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 72
hr
 1235 4053 4513 0.8981 0.8597
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 72
hr
 1235 2970 4513 0.6581 0.5292
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 72
hr
 1235 790 4513 0.1751 -0.1360
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 72
hr
 1235 771 4513 0.1709 -0.1418
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 72
hr
 1235 2602 4513 0.5766 0.4169
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4829 4513 1.0699 1.0962
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 72
hr
 1235 4306 4513 0.9541 0.9368
MDA-MB-231 Foretinib
0.37
uM
LJP5
 72
hr
 1235 1389 4513 0.3079 0.0469
MDA-MB-231 R406
0.37
uM
LJP6
 72
hr
 1235 4314 4513 0.9559 0.9393
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 72
hr
 1235 3275 4513 0.7257 0.6222
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 72
hr
 1235 4443 4513 0.9845 0.9787
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 72
hr
 1235 944 4513 0.2092 -0.0890
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 72
hr
 1235 876 4513 0.1942 -0.1096
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 72
hr
 1235 4112 4513 0.9112 0.8777
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 72
hr
 1235 3933 4513 0.8715 0.8231
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 72
hr
 1235 4087 4513 0.9055 0.8698
MDA-MB-231 Omipalisib
0.37
uM
LJP6
 72
hr
 1235 1155 4513 0.2560 -0.0245
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 72
hr
 1235 4346 4513 0.9630 0.9491
MDA-MB-231 GW843682X
0.37
uM
LJP6
 72
hr
 1235 2103 4513 0.4659 0.2645
MDA-MB-231 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1235 3553 4513 0.7873 0.7071
MDA-MB-231 HG-5-88-01
0.37
uM
LJP6
 72
hr
 1235 3873 4513 0.8582 0.8048
MDA-MB-231 Imatinib
0.37
uM
LJP6
 72
hr
 1235 4366 4513 0.9673 0.9550
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 72
hr
 1235 2281 4513 0.5054 0.3189